[HTML][HTML] Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing

S Patel, S Srivastava, MR Singh, D Singh - Biomedicine & …, 2019 - Elsevier
Wound management in diabetic patient is of an extreme clinical and social concern. The
delayed and impaired healing makes it more critical for research focus. The research on …

[HTML][HTML] Evolving spectrum of diabetic wound: mechanistic insights and therapeutic targets

R Chakraborty, P Borah, PP Dutta… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Diabetes mellitus is a chronic metabolic disorder resulting in an increased blood glucose
level and prolonged hyperglycemia, causes long term health conse-quences. Chronic …

Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes

S Nirenjen, J Narayanan, T Tamilanban… - Frontiers in …, 2023 - frontiersin.org
Background Impaired wound healing is the most common and significant complication of
Diabetes. While most other complications of Diabetes have better treatment options, diabetic …

The problem of wound healing in diabetes—from molecular pathways to the design of an animal model

M Mieczkowski, B Mrozikiewicz-Rakowska… - International journal of …, 2022 - mdpi.com
Chronic wounds are becoming an increasingly common clinical problem due to an aging
population and an increased incidence of diabetes, atherosclerosis, and venous …

Pathogenesis and treatment of impaired wound healing in diabetes mellitus: new insights

D Baltzis, I Eleftheriadou, A Veves - Advances in therapy, 2014 - Springer
Diabetic foot ulcers (DFUs) are one of the most common and serious complications of
diabetes mellitus, as wound healing is impaired in the diabetic foot. Wound healing is a …

Diabetes and wound angiogenesis

UA Okonkwo, LA DiPietro - International journal of molecular sciences, 2017 - mdpi.com
Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in
sight. Complications of DM2 involve a myriad of comorbidities including the serious …

Acellular and cellular approaches to improve diabetic wound healing

H Cho, MR Blatchley, EJ Duh, S Gerecht - Advanced drug delivery reviews, 2019 - Elsevier
Chronic diabetic wounds represent a huge socioeconomic burden for both affected
individuals and the entire healthcare system. Although the number of available treatment …

High-glucose environment disturbs the physiologic functions of keratinocytes: focusing on diabetic wound healing

SCS Hu, CCE Lan - Journal of Dermatological Science, 2016 - Elsevier
Impaired wound healing is a common and potentially serious complication in patients with
diabetes. In recent years, disturbed physiologic functions of epidermal keratinocytes have …

[HTML][HTML] Recent advances on the association of apoptosis in chronic non healing diabetic wound

AK Arya, R Tripathi, S Kumar, K Tripathi - World journal of diabetes, 2014 - ncbi.nlm.nih.gov
Generally, wounds are of two categories, such as chronic and acute. Chronic wounds takes
time to heal when compared to the acute wounds. Chronic wounds include vasculitis, non …

Chronic diabetic wounds and their treatment with skin substitutes

J Holl, C Kowalewski, Z Zimek, P Fiedor, A Kaminski… - Cells, 2021 - mdpi.com
With the global prevalence of type 2 diabetes mellitus steeply rising, instances of chronic,
hard-healing, or non-healing diabetic wounds and ulcers are predicted to increase. The …