Mechanisms of action for antimicrobial peptides with antibacterial and antibiofilm functions

N Raheem, SK Straus - Frontiers in microbiology, 2019 - frontiersin.org
The antibiotic crisis has led to a pressing need for alternatives such as antimicrobial
peptides (AMPs). Recent work has shown that these molecules have great potential not only …

Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations

MN Melo, R Ferre, MARB Castanho - Nature Reviews Microbiology, 2009 - nature.com
An increasing amount of information on the action of antimicrobial peptides (AMPs) at the
molecular level has not yet been translated into a comprehensive understanding of effects in …

Mechanism of antimicrobial peptides: antimicrobial, anti-inflammatory and antibiofilm activities

Y Luo, Y Song - International journal of molecular sciences, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides
antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities …

Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …

Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds

M Erdem Büyükkiraz, Z Kesmen - Journal of applied …, 2022 - academic.oup.com
Antimicrobial peptides (AMPs) are compounds, which have inhibitory activity against
microorganisms. In the last decades, AMPs have become powerful alternative agents that …

Antimicrobial peptides: an introduction

EF Haney, SC Mansour, REW Hancock - Antimicrobial peptides: methods …, 2017 - Springer
The “golden era” of antibiotic discovery has long passed, but the need for new antibiotics
has never been greater due to the emerging threat of antibiotic resistance. This urgency to …

Antimicrobial peptides: interaction with model and biological membranes and synergism with chemical antibiotics

A Hollmann, M Martinez, P Maturana… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown
antimicrobial activity against a wide range of bacterial species, including multiresistant …

Antimicrobial peptides: new candidates in the fight against bacterial infections

O Toke - Peptide Science: Original Research on Biomolecules, 2005 - Wiley Online Library
Antimicrobial peptides (AMPs) of innate origin are agents of the most ancient form of
defense systems. They can be found in a wide variety of species ranging from bacteria …

[HTML][HTML] Chemical modifications to increase the therapeutic potential of antimicrobial peptides

Y Han, M Zhang, R Lai, Z Zhang - Peptides, 2021 - Elsevier
The continued use of antibiotics has been accompanied by the rapid emergence and spread
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …

Development and challenges of antimicrobial peptides for therapeutic applications

CH Chen, TK Lu - Antibiotics, 2020 - mdpi.com
More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …