[HTML][HTML] Engineered vasculature for cancer research and regenerative medicine

HT Nguyen, A Peirsman, Z Tirpakova, K Mandal… - Micromachines, 2023 - mdpi.com
Engineered human tissues created by three-dimensional cell culture of human cells in a
hydrogel are becoming emerging model systems for cancer drug discovery and …

From arteries to capillaries: approaches to engineering human vasculature

S Fleischer, DN Tavakol… - Advanced functional …, 2020 - Wiley Online Library
From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …

[HTML][HTML] Engineering the multiscale complexity of vascular networks

C O'Connor, E Brady, Y Zheng, E Moore… - Nature Reviews …, 2022 - nature.com
The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

Biofabrication strategies for creating microvascular complexity

AM Clyne, S Swaminathan, AD Lantada - Biofabrication, 2019 - iopscience.iop.org
Abstract Design and fabrication of effective biomimetic vasculatures constitutes a relevant
and yet unsolved challenge, lying at the heart of tissue repair and regeneration strategies …

[HTML][HTML] Capillary networks for bio-artificial three-dimensional tissues fabricated using cell sheet based tissue engineering

H Sekine, T Okano - International Journal of Molecular Sciences, 2020 - mdpi.com
One of the most important challenges facing researchers in the field of regenerative
medicine is to develop methods to introduce vascular networks into bioengineered tissues …

[HTML][HTML] Rebuilding the Vascular Network: In vivo and in vitro Approaches

X Meng, Y Xing, J Li, C Deng, Y Li, X Ren… - Frontiers in Cell and …, 2021 - frontiersin.org
As the material transportation system of the human body, the vascular network carries the
transportation of materials and nutrients. Currently, the construction of functional …

[HTML][HTML] 3D biofabrication of vascular networks for tissue regeneration: a report on recent advances

MD Sarker, S Naghieh, NK Sharma, X Chen - Journal of pharmaceutical …, 2018 - Elsevier
Rapid progress in tissue engineering research in past decades has opened up vast
possibilities to tackle the challenges of generating tissues or organs that mimic native …

[HTML][HTML] Advances in hydrogel-based vascularized tissues for tissue repair and drug screening

Y Wang, RK Kankala, C Ou, A Chen, Z Yang - Bioactive materials, 2022 - Elsevier
The construction of biomimetic vasculatures within the artificial tissue models or organs is
highly required for conveying nutrients, oxygen, and waste products, for improving the …

Engineering perfused microvascular networks into microphysiological systems platforms

JW Andrejecsk, CCW Hughes - Current Opinion in Biomedical Engineering, 2018 - Elsevier
The microvasculature is an essential component of nearly all tissues, with most cells
residing within 200 μm of a vessel. Endothelial cells form the inner wall of microvessels and …

Tissue engineering the vascular tree

MA Traore, SC George - Tissue Engineering Part B: Reviews, 2017 - liebertpub.com
A major hurdle in the field of tissue engineering and regenerative medicine remains the
design and construction of larger (> 1 cm3) in vitro tissues for biological studies and …