Short‐term exposure to enriched environment rescues chronic stress‐induced impaired hippocampal synaptic plasticity, anxiety, and memory deficits

VR Bhagya, BN Srikumar, J Veena… - Journal of …, 2017 - Wiley Online Library
Exposure to prolonged stress results in structural and functional alterations in the
hippocampus including reduced long‐term potentiation (LTP), neurogenesis, spatial …

Enriched environment restores hippocampal cell proliferation and ameliorates cognitive deficits in chronically stressed rats

J Veena, BN Srikumar, K Mahati… - Journal of …, 2009 - Wiley Online Library
Adult neurogenesis, particularly in the subgranular zone, is thought to be linked with
learning and memory. Chronic stress inhibits adult hippocampal neurogenesis and also …

Environmental enrichment protects against the effects of chronic stress on cognitive and morphological measures of hippocampal integrity

KM Hutchinson, KJ McLaughlin, RL Wright… - Neurobiology of learning …, 2012 - Elsevier
Chronic stress has detrimental effects on hippocampal integrity, while environmental
enrichment (EE) has beneficial effects when initiated early in development. In this study, we …

Enriched environment experience overcomes the memory deficits and depressive-like behavior induced by early life stress

M Cui, Y Yang, J Yang, J Zhang, H Han, W Ma, H Li… - Neuroscience …, 2006 - Elsevier
Stress in early life is believed to cause cognitive and affective disorders, and to disrupt
hippocampal synaptic plasticity in adolescence into adult, but it is unclear whether exposure …

Enriched environment prevents chronic stress-induced spatial learning and memory deficits

RL Wright, CD Conrad - Behavioural brain research, 2008 - Elsevier
Chronic stress impairs spatial memory and alters hippocampal structure, which are changed
in the opposite direction following enriched environment (EE). Therefore, this study …

Enriched environment ameliorates depression-induced cognitive deficits and restores abnormal hippocampal synaptic plasticity

K Mahati, V Bhagya, T Christofer, A Sneha… - Neurobiology of learning …, 2016 - Elsevier
Severe depression compromises structural and functional integrity of the brain and results in
impaired learning and memory, maladaptive synaptic plasticity as well as degenerative …

Environmental enrichment ameliorates chronic immobilisation stress-induced spatial learning deficits and restores the expression of BDNF, VEGF, GFAP and …

BM Shilpa, V Bhagya, G Harish, MMS Bharath… - Progress in Neuro …, 2017 - Elsevier
Severe and prolonged stress is the main environmental factor that precipitates depression,
anxiety and cognitive dysfunctions. On the other hand, exposure to environmental …

Enriched environment treatment restores impaired hippocampal synaptic plasticity and cognitive deficits induced by prenatal chronic stress

J Yang, C Hou, N Ma, J Liu, Y Zhang, J Zhou… - Neurobiology of learning …, 2007 - Elsevier
Prenatal stress can cause long-term effects on cognitive functions in offspring. Hippocampal
synaptic plasticity, believed to be the mechanism underlying certain types of learning and …

Self-stimulation rewarding experience restores stress-induced CA3 dendritic atrophy, spatial memory deficits and alterations in the levels of neurotransmitters in the …

K Ramkumar, BN Srikumar… - Neurochemical …, 2008 - Springer
Chronic restraint stress causes spatial learning and memory deficits, dendritic atrophy of the
hippocampal pyramidal neurons and alterations in the levels of neurotransmitters in the …

The stress experience dependent long-term depression disassociated with stress effect on spatial memory task

W Xiong, Y Yang, J Cao, H Wei, C Liang, S Yang… - Neuroscience …, 2003 - Elsevier
Behavioral stress can either block or facilitate memory and affect the induction of long-term
potentiation (LTP) and long-term depression (LTD). However, the relevance of the stress …