The purpose of this study was to determine the toxicological and pharmacokinetic properties
of sucralose-6-acetate, a structural analog of the artificial sweetener sucralose. Sucralose-6 …

Sucralose is a non-nutritive sweetener that is approximately 600 times sweeter than table
sugar. It is currently approved for use in over 80 countries. Evidence from chronic studies …

Two tolerance studies were conducted in healthy human adult volunteers. The first study
was an ascending dose study conducted in eight subjects, in which sucralose was …

Sucralose is a non-caloric high intensity sweetener that is approved globally for use in foods
and beverages. This review provides an updated summary of the literature addressing the …

The purpose of this overview is to outline the general toxicological observations seen during
the course of the development of sucralose, the nonnutritive, high-intensity sweetener. The …

Regulatory authorities worldwide have found the nonnutritive sweetener, sucralose, to be
noncarcinogenic, based on a range of studies. A review of these and other studies found …

The aim of this study was to (1) determine if the organochlorine artificial sweetener
sucralose is metabolized in rat intestine with repeated dosing and (2) examine whether …

The chronic toxicity and potential carcinogenicity of sucralose was evaluated by exposing
Sprague–Dawley rats to dietary concentrations of this low-calorie sweetener both in utero …

The toxicity of sucralose has been evaluated in acute and subchronic toxicity studies. Acute
oral toxicity studies in male and female mice and male rats documented no deaths or …

Sucralose is a non-nutritive sweetener used in a broad range of foods and beverages and is
the non-nutritive sweetener in retail SPLENDA® Sweetening Products, composed of …