Tumour necrosis factor (TNF)‐mediated signalling plays a key role in inflammatory and
neurodegenerative processes leading to the development of multiple sclerosis (MS). Recent …

Objectives: To investigate the roles of 2 polymorphisms of the tumor necrosis factor (TNF)
receptor superfamily member 1A (TNFRSF1A) gene, rs1800693 (a common variant) and …

Dysregulation in the expression of pro‐and anti‐inflammatory cytokines is one of the
milestones in multiple sclerosis (MS) development and progression. Tumour necrosis factor …

ABSTRACT TNF-α is an important cytokine of the inflammatory response involved in the
pathogenesis of relapsing-remitting multiple sclerosis (RRMS). The aim of this study is to …

Tumor necrosis factor (TNF) α has been considered the prototypic cytopathogenic cytokine
in multiple sclerosis (MS), but recently this cytokine has been shown to possess significant …

Tumor necrosis factor (TNF)-f and TNF-g are proinflammatory cytokines that have been
implicated in the pathogenesis of several autoimmune diseases. The aim of this …

Multiple sclerosis (MS) is a complex polygenic disease in which gene-environment
interactions are important. A number of studies have investigated the association between …

Objective–To investigate the association between tumor necrosis factor‐α (TNF‐α) G‐308A,
tumor necrosis factor‐β (TNF‐β) G+ 252A and interleukin‐4 (IL‐4) C‐590T polymorphisms …

Variations in two genes of the tumour necrosis factor (TNF) alpha pathway have been
implicated in the pathogenesis of autoimmune diseases: polymorphisms in the TNFRSF 1A …

Multiple Sclerosis is a chronic neuro-immune disorder of the central CNS. MS belongs to the
large group of multifactorial and multi-genic disease. The TNFα gene encodes pro …