In eukaryotes, the separation of translation from transcription by the nuclear envelope
enables mRNA modifications such as capping, splicing, and polyadenylation. These …

Eukaryotic gene expression is controlled by multiple mechanisms, and its regulation is
central for physiological responses to extracellular and intracellular signals. An essential …

A defining feature of eukaryotic cells is the presence of a nuclear envelope separating
transcription and DNA replication in the nucleus from the site of protein synthesis in the …

mRNAs are transported from the nucleus to the cytoplasm by a machinery conserved from
yeast to humans. Previous studies showed that mRNA export factors are loaded on nascent …

The advent of the nucleus during the evolutionary development of the eukaryotic cell
necessitated the development of a transport system to convey messenger RNA (mRNA) from …

One of the most profound differences between prokaryotes and eukaryotes is that only the
latter segregate RNA synthesis and protein synthesis into distinct cellular compartments, ie …

Regulation of gene expression can occur at many different levels. One important step in the
gene expression process is the transport of mRNA from the nucleus to the cytoplasm. In …

Following transcription and processing, eukaryotic mRNAs are exported from the nucleus to
the cytoplasm for translation. Here we present evidence that mRNAs are targeted for nuclear …

Cellular mRNAs are produced in the nucleus and must be exported to the cytoplasm to allow
for their translation into proteins. Recruitment of export factors to nascent mRNA starts …

Eukaryotic cells export several different classes of RNA molecule from the nucleus, where
they are transcribed, to the cytoplasm, where the majority participate in different aspects of …