[HTML][HTML] Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease
F Liew, C Efstathiou, S Fontanella, M Richardson… - Nature …, 2024 - nature.com
One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged
symptoms termed long coronavirus disease (COVID), yet disease phenotypes and …
symptoms termed long coronavirus disease (COVID), yet disease phenotypes and …
[HTML][HTML] Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae
RC Thompson, NW Simons, L Wilkins, E Cheng… - Nature Medicine, 2023 - nature.com
Post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection are debilitating, clinically heterogeneous and of unknown molecular etiology. A …
infection are debilitating, clinically heterogeneous and of unknown molecular etiology. A …
[HTML][HTML] Divergent adaptive immune responses define two types of long COVID
J Kervevan, I Staropoli, D Slama… - Frontiers in …, 2023 - frontiersin.org
Background The role of adaptive immune responses in long COVID remains poorly
understood, with contrasting hypotheses suggesting either an insufficient antiviral response …
understood, with contrasting hypotheses suggesting either an insufficient antiviral response …
[HTML][HTML] Persistent serum protein signatures define an inflammatory subcategory of long COVID
Long COVID or post-acute sequelae of SARS-CoV-2 (PASC) is a clinical syndrome featuring
diverse symptoms that can persist for months following acute SARS-CoV-2 infection. The …
diverse symptoms that can persist for months following acute SARS-CoV-2 infection. The …
[HTML][HTML] Distinguishing features of Long COVID identified through immune profiling
Post-acute infection syndromes may develop after acute viral disease. Infection with SARS-
CoV-2 can result in the development of a post-acute infection syndrome known as long …
CoV-2 can result in the development of a post-acute infection syndrome known as long …
[HTML][HTML] Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection
Coordinated local mucosal and systemic immune responses following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against …
Immune signatures underlying post-acute COVID-19 lung sequelae
Severe coronavirus disease 2019 (COVID-19) pneumonia survivors often exhibit long-term
pulmonary sequelae, but the underlying mechanisms or associated local and systemic …
pulmonary sequelae, but the underlying mechanisms or associated local and systemic …
Prolonged inflammation in patients hospitalized for coronavirus disease 2019 (COVID‐19) resolves 2 years after infection
Long‐term complications from coronavirus disease 2019 (COVID‐19) are concerning, as
survivors can develop subclinical multiorgan dysfunction. It is unknown if such complications …
survivors can develop subclinical multiorgan dysfunction. It is unknown if such complications …
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19
RS Thwaites, A Sanchez Sevilla Uruchurtu… - Science …, 2021 - science.org
While it is now widely accepted that host inflammatory responses contribute to lung injury,
the pathways that drive severity and distinguish coronavirus disease 2019 (COVID-19) from …
the pathways that drive severity and distinguish coronavirus disease 2019 (COVID-19) from …
[HTML][HTML] Early immune factors associated with the development of post-acute sequelae of SARS-CoV-2 infection in hospitalized and non-hospitalized individuals
JM Leung, MJ Wu, P Kheradpour, C Chen… - Frontiers in …, 2024 - frontiersin.org
Background Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
can lead to post-acute sequelae of SARS-CoV-2 (PASC) that can persist for weeks to years …
can lead to post-acute sequelae of SARS-CoV-2 (PASC) that can persist for weeks to years …