Angiopoietin 2 and cardiovascular disease in dialysis and kidney transplantation
S David, P Kümpers, J Hellpap, R Horn, H Leitolf… - American Journal of …, 2009 - Elsevier
BACKGROUND: Accelerated atherosclerosis in patients with chronic kidney disease (CKD)
is still incompletely understood. Angiopoietin 1 (Ang-1) and Ang-2 are 55-kDa antagonistic …
is still incompletely understood. Angiopoietin 1 (Ang-1) and Ang-2 are 55-kDa antagonistic …
Circulating angiopoietin-2 levels increase with progress of chronic kidney disease
S David, P Kümpers, A Lukasz, D Fliser… - Nephrology Dialysis …, 2010 - academic.oup.com
Abstract Background. Angiopoietin-2 (Ang-2) is an antagonistic ligand of the endothelial-
specific Tie2 receptor. Patients on dialysis have markedly elevated Ang-2 levels, and those …
specific Tie2 receptor. Patients on dialysis have markedly elevated Ang-2 levels, and those …
Angiopoietin-2 levels predict mortality in CKD patients
S David, SG John, HJ Jefferies… - Nephrology Dialysis …, 2012 - academic.oup.com
Background. The pathophysiology of aggravated atherosclerosis in chronic kidney disease
(CKD) is still incompletely understood. However, there is an increasing focus on non …
(CKD) is still incompletely understood. However, there is an increasing focus on non …
High plasma angiopoietin-2 levels predict the need to initiate dialysis within two years in patients with chronic kidney disease
A Szymczak, M Kusztal, T Gołębiowski… - International Journal of …, 2023 - mdpi.com
Volume status, congestion, endothelial activation, and injury all play roles in glomerular
filtration rate (GFR) decline. In this study, we aimed to determine whether the plasma …
filtration rate (GFR) decline. In this study, we aimed to determine whether the plasma …
Association of angiopoietin-2 with renal outcome in chronic kidney disease
Background The pathophysiological mechanisms of renal function progression in chronic
kidney disease (CKD) have still not been completely explored. In addition to well-known …
kidney disease (CKD) have still not been completely explored. In addition to well-known …
Angiopoietin-2 as a prognostic biomarker of major adverse cardiovascular events and all-cause mortality in chronic kidney disease
YC Tsai, CS Lee, YW Chiu, HT Kuo, SC Lee… - PloS one, 2015 - journals.plos.org
Background Chronic kidney disease (CKD) patients have higher prevalence of major
adverse cardiovascular events (MACE) and all-cause mortality. Endothelial damage and …
adverse cardiovascular events (MACE) and all-cause mortality. Endothelial damage and …
Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease
YC Tsai, CS Lee, YW Chiu, HT Kuo, SC Lee… - Scientific reports, 2016 - nature.com
Angiopoietins (Angpt) and vascular endothelial growth factor (VEGF) have been associated
with cardiovascular disease. The study enrolled 270 pre-dialysis stage 3–5 CKD patients to …
with cardiovascular disease. The study enrolled 270 pre-dialysis stage 3–5 CKD patients to …
Angiopoietin-2 is associated with albuminuria and microinflammation in chronic kidney disease
Although cardiovascular disease (CVD) is the leading cause of mortality in patients with
chronic kidney disease (CKD), the pathophysiology is not thoroughly understood. Given that …
chronic kidney disease (CKD), the pathophysiology is not thoroughly understood. Given that …
Circulating angiopoietin-2 in essential hypertension: relation to atherosclerosis, vascular inflammation, and treatment with olmesartan/pravastatin
S David, P Kümpers, A Lukasz, JT Kielstein… - Journal of …, 2009 - journals.lww.com
Background Endothelial activation has emerged as an early event in the pathogenesis of
cardiovascular disease. Angiopoietin-2 (Ang-2) has been identified as a nonredundant …
cardiovascular disease. Angiopoietin-2 (Ang-2) has been identified as a nonredundant …
Circulating angiopoietin-2 is a marker for early cardiovascular disease in children on chronic dialysis
Cardiovascular disease (CVD) is increasingly recognised as a complication of childhood
chronic kidney disease (CKD) even in the absence of diabetes and hypertension. We …
chronic kidney disease (CKD) even in the absence of diabetes and hypertension. We …
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