Human Mesenchymal Stem Cell (hMSC) immunotherapy has been shown to provide both
anti-inflammatory and anti-microbial effectiveness in a variety of diseases. The clinical …

Human Mesenchymal stem cells (hMSCs) secrete products (supernatants) that are anti-
inflammatory and antimicrobial. We have previously shown that hMSCs decrease …

Cystic fibrosis (CF) is a genetic disease in which the battle between pulmonary infection and
inflammation becomes the major cause of morbidity and mortality. We have previously …

Cystic fibrosis (CF) is a genetically inherited disease which is characterized by excessive
inflammation and inability to resolve infection with pathogens such as Pseudomonas …

Background Mesenchymal stem cells are of particular interest in cystic fibrosis (CF) as a
potential therapeutic. Data from pre-clinical studies suggest that allogeneic bone marrow …

In cystic fibrosis (CF), sustained infection and exuberant inflammation results in debilitating
and often fatal lung disease. Advancement in CF therapeutics has provided successful …

Mesenchymal stem cells (MSCs) are multipotent non-hematopoietic stem cells residing in
many tissues, including the lung. MSCs have long been regarded as a promising tool for cell …

Mesenchymal stem cells (MSCs) have gained widespread use in regenerative medicine due
to their demonstrated efficacy in a broad range of experimental animal models of disease …

Introduction: Cystic fibrosis (CF) is a genetic syndrome with a high mortality rate due to
severe lung disease. Despite having several drugs targeting specific mutated CFTR proteins …

The past decade has seen tremendous growth in the clinical application of cell-based
therapies, and the number of planned human clinical trials to evaluate these therapies …