Dietary compounds as epigenetic modulating agents in cancer

Á Carlos-Reyes, JS López-González… - Frontiers in …, 2019 - frontiersin.org
Epigenetic mechanisms control gene expression during normal development and their
aberrant regulation may lead to human diseases including cancer. Natural phytochemicals …

Epigenetic regulation by selected dietary phytochemicals in cancer chemoprevention

S Shukla, SM Meeran, SK Katiyar - Cancer letters, 2014 - Elsevier
The growing interest in cancer epigenetics is largely due to the reversible nature of
epigenetic changes which tend to alter during the course of carcinogenesis. Major …

Epigenetic modifications by dietary phytochemicals: implications for personalized nutrition

S Shankar, D Kumar, RK Srivastava - Pharmacology & therapeutics, 2013 - Elsevier
In the last two decades, the study of epigenetic modification emerged as one of the major
areas of cancer treatment targeted by dietary phytochemicals. Recent studies with various …

Epigenetic targets of bioactive dietary components for cancer prevention and therapy

SM Meeran, A Ahmed, TO Tollefsbol - Clinical epigenetics, 2010 - Springer
The emergent interest in cancer epigenetics stems from the fact that epigenetic modifications
are implicated in virtually every step of tumorigenesis. More interestingly, epigenetic …

Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges

E Shankar, R Kanwal, M Candamo, S Gupta - Seminars in cancer biology, 2016 - Elsevier
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …

Plant phytochemicals as epigenetic modulators: role in cancer chemoprevention

VS Thakur, G Deb, MA Babcook, S Gupta - The AAPS journal, 2014 - Springer
In recent years,“nutri-epigenetics,” which focuses on the influence of dietary agents on
epigenetic mechanism (s), has emerged as an exciting novel area in epigenetics research …

Polyphenols as potent epigenetics agents for cancer

P Rajendran, SA Abdelsalam, K Renu… - International journal of …, 2022 - mdpi.com
Human diseases such as cancer can be caused by aberrant epigenetic regulation.
Polyphenols play a major role in mammalian epigenome regulation through mechanisms …

Epigenetic mechanisms in anti‐cancer actions of bioactive food components–the implications in cancer prevention

B Stefanska, H Karlic, F Varga… - British journal of …, 2012 - Wiley Online Library
The hallmarks of carcinogenesis are aberrations in gene expression and protein function
caused by both genetic and epigenetic modifications. Epigenetics refers to the changes in …

Cancer chemoprevention and nutri-epigenetics: state of the art and future challenges

C Gerhauser - Natural products in cancer prevention and therapy, 2013 - Springer
The term “epigenetics” refers to modifications in gene expression caused by heritable, but
potentially reversible, changes in DNA methylation and chromatin structure. Epigenetic …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …