The total synthesis and biological evaluation of the marine sesterterpenoid ansellone A (1),
an HIV latency-reversing agent, and its analogues are reported. The key to the success of …

Structurally simplified analogues of ansellone A, in which the decalin skeleton is replaced
with a lipophilic chain, were prepared and their HIV latency‐reversing activities biologically …

The first total synthesis of marine sesterterpenoid ansellone G (2) was accomplished. This
strategy utilizes the Prins cyclization reaction of a chloro-substituted homoallyl alcohol to …

Five new minor sesterterpenoids, ansellones H (4), I (5), J (6), and K (7) and phorone C (8),
have been isolated from a Phorbas sp. marine sponge collected in British Columbia. Their …

Eight new sesterterpenoids, alotaketals D (8) and E (9), ansellones D (10), E (11), F (12),
and G (13), and anvilones A (14) and B (15), have been isolated from extracts of the marine …

Three new diterpenes, stellejasmins A (1) and B (2) and 12-O-benzoylphorbol-13-
heptanoate (3), were isolated from the roots of Stellera chamaejasme L. The structures of 1 …

Reported here is the synthesis of the leishmanicidal and trypanocidal monoterpene
espintanol (1) in 64% overall yield starting with dimethyl squarate. This antiparasitic …

Forty-two dihydroseselins based on the structure of suksdorfin (1) were synthesized in order
to evaluate their anti-HIV activity. These synthetic derivatives include 3', 4'-di-0-acyl-and 3'-or …

Natural products originating from marine and plant materials are a rich source of chemical
diversity and unique antimicrobials. Using an established in vitro model of HIV-1 latency, we …

We report short syntheses of (−)-tripterifordin and (−)-neotripterifordin, potent inhibitors of
HIV replication, from stevioside, a natural sweetener used worldwide. The key …