Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A …
Polycyclic aromatic hydrocarbons (PAHs) derived from fossil fuels are ubiquitous
contaminants and occur in aquatic habitats as highly variable and complex mixtures of …
contaminants and occur in aquatic habitats as highly variable and complex mixtures of …
The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish
SM Billiard, AR Timme-Laragy… - Toxicological …, 2006 - academic.oup.com
Planar halogenated aromatic hydrocarbons (pHAHs), such as 2, 3, 7, 8-tetrachlorodibenzo-p-
dioxin (dioxin), show strong binding affinity for the aryl hydrocarbon receptor (AHR) and are …
dioxin (dioxin), show strong binding affinity for the aryl hydrocarbon receptor (AHR) and are …
Synergistic induction of AHR regulated genes in developmental toxicity from co-exposure to two model PAHs in zebrafish
AR Timme-Laragy, CJ Cockman, CW Matson… - Aquatic toxicology, 2007 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are pollutants created by the incomplete
combustion of carbon, and are increasing in the environment largely due to the burning of …
combustion of carbon, and are increasing in the environment largely due to the burning of …
AHR2 knockdown prevents PAH-mediated cardiac toxicity and XRE-and ARE-associated gene induction in zebrafish (Danio rerio)
LA Van Tiem, RT Di Giulio - Toxicology and applied pharmacology, 2011 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants often
present in aquatic systems as complex mixtures. Embryonic fish are sensitive to the …
present in aquatic systems as complex mixtures. Embryonic fish are sensitive to the …
Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish
BC Goodale, SC Tilton, MM Corvi, GR Wilson… - Toxicology and applied …, 2013 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components
of fossil fuels and by-products of combustion. These multi-ring chemicals differentially …
of fossil fuels and by-products of combustion. These multi-ring chemicals differentially …
Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish development
Petroleum-derived compounds, including polycyclic aromatic hydrocarbons (PAHs),
commonly occur as complex mixtures in the environment. Recent studies using the zebrafish …
commonly occur as complex mixtures in the environment. Recent studies using the zebrafish …
Low-level pyrene exposure causes cardiac toxicity in zebrafish (Danio rerio) embryos
Y Zhang, C Wang, L Huang, R Chen, Y Chen, Z Zuo - Aquatic toxicology, 2012 - Elsevier
It is widely accepted that the most abundant polycyclic aromatic hydrocarbons (PAHs) in
weathered crude oils is cardiotoxic. Although PAHs toxic endpoints show strong correlation …
weathered crude oils is cardiotoxic. Although PAHs toxic endpoints show strong correlation …
Binding of polycyclic aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs)
SM Billiard, ME Hahn, DG Franks, RE Peterson… - … and physiology part B …, 2002 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous, environmental contaminants that
pose a potential risk to fish populations. Both field and laboratory studies suggest that …
pose a potential risk to fish populations. Both field and laboratory studies suggest that …
AHR2-mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs
N Jayasundara, L Van Tiem Garner… - Toxicological …, 2015 - academic.oup.com
Polycyclic aromatic hydrocarbons (PAHs) induce developmental defects including cardiac
deformities in fish. The aryl hydrocarbon receptor (AHR) mediates the toxicity of some PAHs …
deformities in fish. The aryl hydrocarbon receptor (AHR) mediates the toxicity of some PAHs …
Synergistic Embryotoxicity of Polycyclic Aromatic Hydrocarbon Aryl Hydrocarbon Receptor Agonists with Cytochrome P4501A Inhibitors in Fundulus heteroclitus
DM Wassenberg, RT Di Giulio - Environmental health …, 2004 - ehp.niehs.nih.gov
Widespread contamination of aquatic systems with polycyclic aromatic hydrocarbons (PAHs)
has led to concern about effects of PAHs on aquatic life. Some PAHs have been shown to …
has led to concern about effects of PAHs on aquatic life. Some PAHs have been shown to …