Curcumin, a polyphenolic curcuminoid with its protective effects and molecular mechanisms in diabetes and diabetic cardiomyopathy

J Zheng, J Cheng, S Zheng, Q Feng… - Frontiers in …, 2018 - frontiersin.org
As the leading cause of morbidity and mortality in patients with diabetes, diabetic
cardiomyopathy (DCM) imposes enormous burden on individuals and public health …

Tiny molecule, big power: multi-target approach for curcumin in diabetic cardiomyopathy

V Karuppagounder, S Arumugam, VV Giridharan… - Nutrition, 2017 - Elsevier
Diabetic cardiomyopathy (DCM) is described as impaired cardiac diastolic and systolic
functions. Diabetes mellitus (DM), a related cardiovascular disease, has become one of the …

Curcumin, the golden spice in treating cardiovascular diseases

H Li, A Sureda, HP Devkota, V Pittalà, D Barreca… - Biotechnology …, 2020 - Elsevier
Cardiovascular diseases (CVDs) cause the largest mortality worldwide, and much attention
has been focused to unravel the mechanisms and optimize the treatment regimens …

[HTML][HTML] Curcumin and cardiovascular diseases: Focus on cellular targets and cascades

AM Pourbagher-Shahri, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
Cardiovascular diseases (CVDs) are one of the leading causes of the most considerable
mortality globally, and it has been tried to find the molecular mechanisms and design new …

Curcumin alleviates diabetic cardiomyopathy in experimental diabetic rats

W Yu, J Wu, F Cai, J Xiang, W Zha, D Fan, S Guo… - PloS one, 2012 - journals.plos.org
Objectives Diabetic cardiomyopathy (DCM), characterized by myocardial structural and
functional changes, is an independent cardiomyopathy that develops in diabetic individuals …

Curcumin and type 2 diabetes mellitus: prevention and treatment

F Pivari, A Mingione, C Brasacchio, L Soldati - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is an ensemble of metabolic diseases that has reached
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …

Curcumin as a potential protective compound against cardiac diseases

S Jiang, J Han, T Li, Z Xin, Z Ma, W Di, W Hu… - Pharmacological …, 2017 - Elsevier
Curcumin, which was first used 3000 years ago as an anti-inflammatory agent, is a well-
known bioactive compound derived from the active ingredient of turmeric (Curcuma longa) …

Protective effects of curcumin in cardiovascular diseases—Impact on oxidative stress and mitochondria

FF Cox, A Misiou, A Vierkant, N Ale-Agha, M Grandoch… - Cells, 2022 - mdpi.com
Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …

Curcumin: a natural product for diabetes and its complications

S Fazel Nabavi, R Thiagarajan… - Current topics in …, 2015 - ingentaconnect.com
Curcumin is the yellow-colored bioactive constituent of the perennial plant, Curcuma longa
L., which possesses a wide range of physiological and pharmacological properties such as …

[HTML][HTML] Utility of curcumin for the treatment of diabetes mellitus: evidence from preclinical and clinical studies

S Rivera-Mancía, J Trujillo, JP Chaverri - Journal of Nutrition & Intermediary …, 2018 - Elsevier
Turmeric or Curcuma longa is a natural product, whose medicinal properties have been
extensively studied and a wide variety of therapeutic effects on several diseases such as …