Diabetes mellitus (DM) displays a high morbidity. The diabetic heart is susceptible to
myocardial ischemia/reperfusion (MI/R) injury. Impaired activation of prosurvival pathways …

Oxidative and reductive stress are dual dynamic phases experienced by the cells
undergoing adaptation towards endogenous or exogenous noxious stimulus. The former …

As a serious cardiovascular complication, diabetic cardiomyopathy (DCM) refers to diabetes‐
related changes in myocardial structure and function, which is obviously different from those …

Myocardial ischemia is a disease with high morbidity and mortality, for which reperfusion is
currently the standard intervention. However, the reperfusion may lead to further myocardial …

Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …

The risk factors, such as hypertension and metabolic syndrome, tend to promote heart
pathology. These risk factors can aggravate concomitant heart insults as well. Diabetes …

Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …

Cardiovascular disease is the most common cause of death in the diabetic population and is
currently one of the leading causes of death in the United States and other industrialized …

Cardiac dysfunction occurs during type 1 and type 2 diabetes and results from multiple
parameters including glucotoxicity, lipotoxicity, fibrosis and mitochondrial uncoupling …

Enhancing mitochondrial biogenesis and reducing mitochondrial oxidative stress have
emerged as crucial therapeutic strategies to ameliorate diabetic myocardial …