[HTML][HTML] Development and research progress of anti-drug resistant fungal drugs
X Cui, L Wang, Y Lue, C Yue - Journal of Infection and Public Health, 2022 - Elsevier
With the widespread use of immunosuppressive agents and the increase in patients with
severe infections, the incidence of fungal infections worldwide has increased year by year …
severe infections, the incidence of fungal infections worldwide has increased year by year …
Potential targets for the development of new antifungal drugs
H Su, L Han, X Huang - The journal of antibiotics, 2018 - nature.com
In recent years, incidences of invasive fungal infections have greatly increased, especially in
immunosuppressed patients, but most today's antifungal drugs are not completely effective …
immunosuppressed patients, but most today's antifungal drugs are not completely effective …
Antifungals and drug resistance
Definition Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …
How urgent is the need for new antifungals?
AG Stewart, DL Paterson - Expert Opinion on Pharmacotherapy, 2021 - Taylor & Francis
Introduction: Invasive fungal infection carries a high morbidity, mortality and economic cost.
In recent times, a rising incidence of fungal infection and antifungal resistance is occurring …
In recent times, a rising incidence of fungal infection and antifungal resistance is occurring …
Novel agents and drug targets to meet the challenges of resistant fungi
MW McCarthy, DP Kontoyiannis… - The Journal of …, 2017 - academic.oup.com
The emergence of drug-resistant fungi poses a major threat to human health. Despite
advances in preventive, diagnostic, and therapeutic interventions, resistant fungal infections …
advances in preventive, diagnostic, and therapeutic interventions, resistant fungal infections …
New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
J Geddes‐McAlister, RS Shapiro - … of the New York Academy of …, 2019 - Wiley Online Library
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …
along with significant agricultural crop loss caused by various fungal species, has resulted in …
Antifungal drugs: the current armamentarium and development of new agents
Invasive fungal infections are becoming an increasingly important cause of human mortality
and morbidity, particularly for immunocompromised populations. The fungal pathogens …
and morbidity, particularly for immunocompromised populations. The fungal pathogens …
Emerging issues in antifungal resistance
JR Perfect, M Ghannoum - Infectious Disease Clinics, 2020 - id.theclinics.com
This review attempts to frame the issues around antifungal drug resistance. From its
epidemiology, mechanisms, measurements, and clinical significance, invasive fungal …
epidemiology, mechanisms, measurements, and clinical significance, invasive fungal …
Recent progress on antifungal drug development
Invasive fungal infections are a serious threat to public health, particularly to people with
compromised or suppressed immunity. Although the current antifungal therapies have been …
compromised or suppressed immunity. Although the current antifungal therapies have been …