Background Without knowledge of their genomic sequences, it is impossible to make
functional models of the bacteria that make up human and animal microbiota. Unfortunately …

The oral cavity of each person is home to hundreds of bacterial species. While taxa for oral
diseases have been studied using culture-based characterization as well as amplicon …

In their recent study, Espinoza et al. employ genome-resolved metagenomics to investigate
supragingival plaque metagenomes of 88 individuals (1). The 34 metagenome-assembled …

Although biofilms have been shown to be reservoirs of pathogens, our knowledge of the
microbial diversity in biofilms within critical areas, such as health care facilities, is limited …

Background The increasing availability of microbial genomes and environmental shotgun
metagenomes provides unprecedented access to the genomic differences within related …

Shotgun short-read sequencing methods facilitate study of the genomic content and strain-
level architecture of complex microbial communities. However, existing methodologies do …

Here we present the draft genome of a distantly related member within the phylum
Bacteriodetes,“Candidatus Bacteroides periocalifornicus.” The draft genome sequence was …

Porphyromonas gingivalis is associated with both oral and systemic diseases. Strain-
specific P. gingivalis invasion phenotypes do not reliably predict disease presentation …

Background Sequencing of the 16S rRNA gene has been the standard for studying the
composition of microbial communities. While it allows identification of bacteria at the level of …

Among the human health conditions linked to microbial communities, phenotypes are often
associated with only a subset of strains within causal microbial groups. Although it has been …