Biosynthesis of cis,cis-Muconic Acid and Its Aromatic Precursors, Catechol and Protocatechuic Acid, from Renewable Feedstocks by Saccharomyces cerevisiae

C Weber, C Brückner, S Weinreb, C Lehr… - Applied and …, 2012 - Am Soc Microbiol
Adipic acid is a high-value compound used primarily as a precursor for the synthesis of
nylon, coatings, and plastics. Today it is produced mainly in chemical processes from …

Metabolic engineering of muconic acid production in Saccharomyces cerevisiae

KA Curran, JM Leavitt, AS Karim, HS Alper - Metabolic engineering, 2013 - Elsevier
The dicarboxylic acid muconic acid has garnered significant interest due to its potential use
as a platform chemical for the production of several valuable consumer bio-plastics …

Benzene‐free synthesis of adipic acid

W Niu, KM Draths, JW Frost - Biotechnology progress, 2002 - Wiley Online Library
Strains of Escherichia coli were constructed and evaluated that synthesized cis, cis‐muconic
acid from d‐glucose under fed‐batch fermentor conditions. Chemical hydrogenation of the …

A novel muconic acid biosynthesis approach by shunting tryptophan biosynthesis via anthranilate

X Sun, Y Lin, Q Huang, Q Yuan… - Applied and environmental …, 2013 - Am Soc Microbiol
Muconic acid is the synthetic precursor of adipic acid, and the latter is an important platform
chemical that can be used for the production of nylon-6, 6 and polyurethane. Currently, the …

An expanded enzyme toolbox for production of cis, cis-muconic acid and other shikimate pathway derivatives in Saccharomyces cerevisiae

C Brückner, M Oreb, G Kunze, E Boles… - FEMS yeast …, 2018 - academic.oup.com
A wide range of commercially relevant aromatic chemicals can be synthesized via the
shikimic acid pathway. Thus, this pathway has been the target of diverse metabolic …

An Engineered Aro1 Protein Degradation Approach for Increased cis,cis-Muconic Acid Biosynthesis in Saccharomyces cerevisiae

ME Pyne, L Narcross, M Melgar, K Kevvai… - Applied and …, 2018 - Am Soc Microbiol
Muconic acid (MA) is a chemical building block and precursor to adipic and terephthalic
acids used in the production of nylon and polyethylene terephthalate polymer families …

Biosensor‐Enabled Directed Evolution to Improve Muconic Acid Production in Saccharomyces cerevisiae

JM Leavitt, JM Wagner, CC Tu, A Tong… - Biotechnology …, 2017 - Wiley Online Library
Muconic acid is a valuable platform chemical with potential applications in the production of
polymers such as nylon and polyethylene terephthalate (PET). The conjugate base …

[HTML][HTML] Tailoring strain construction strategies for muconic acid production in S. cerevisiae and E. coli

NJH Averesch, JO Krömer - Metabolic engineering communications, 2014 - Elsevier
There is currently a strong interest to derive the biological precursor cis, cis-muconic acid
from shikimate pathway-branches to develop a biological replacement for adipic acid …

Metabolic engineering of Corynebacterium glutamicum for the production of cis, cis-muconic acid from lignin

J Becker, M Kuhl, M Kohlstedt, S Starck… - Microbial cell …, 2018 - Springer
Background Cis, cis-muconic acid (MA) is a dicarboxylic acid of recognized industrial value.
It provides direct access to adipic acid and terephthalic acid, prominent monomers of …

Improvement of cis,cis-Muconic Acid Production in Saccharomyces cerevisiae through Biosensor-Aided Genome Engineering

G Wang, S Øzmerih, R Guerreiro… - ACS synthetic …, 2020 - ACS Publications
Muconic acid is a potential platform chemical for the production of nylon, polyurethanes, and
terephthalic acid. It is also an attractive functional copolymer in plastics due to its two double …