Mechanics, mechanobiology, and modeling of human abdominal aorta and aneurysms

JD Humphrey, GA Holzapfel - Journal of biomechanics, 2012 - Elsevier
Biomechanical factors play fundamental roles in the natural history of abdominal aortic
aneurysms (AAAs) and their responses to treatment. Advances during the past two decades …

Biomechanical investigation of disturbed hemodynamics-induced tissue degeneration in abdominal aortic aneurysms using computational and experimental …

HE Salman, B Ramazanli, MM Yavuz… - … in bioengineering and …, 2019 - frontiersin.org
Abdominal aortic aneurysm (AAA) is the dilatation of the aorta beyond 50% of the normal
vessel diameter. It is reported that 4–8% of men and 0.5–1% of women above 50 years of …

Importance of initial aortic properties on the evolving regional anisotropy, stiffness and wall thickness of human abdominal aortic aneurysms

JS Wilson, S Baek… - Journal of The Royal …, 2012 - royalsocietypublishing.org
Complementary advances in medical imaging, vascular biology and biomechanics promise
to enable computational modelling of abdominal aortic aneurysms to play increasingly …

Biomechanics of abdominal aortic aneurysm

DA Vorp - Journal of biomechanics, 2007 - Elsevier
Abdominal aortic aneurysm (AAA) is a condition whereby the terminal aorta permanently
dilates to dangerous proportions, risking rupture. The biomechanics of AAA has been …

Evolving mechanical properties of a model of abdominal aortic aneurysm

PN Watton, NA Hill - Biomechanics and modeling in mechanobiology, 2009 - Springer
The novel three-dimensional (3D) mathematical model for the development of abdominal
aortic aneurysm (AAA) of Watton et al. Biomech Model Mechanobiol 3 (2): 98–113,(2004) …

[HTML][HTML] Mechanical deterioration underlies malignant behavior of aneurysmal human ascending aorta

G Koullias, R Modak, M Tranquilli, DP Korkolis… - The Journal of thoracic …, 2005 - Elsevier
OBJECTIVE: The human ascending aorta becomes markedly prone to rupture and
dissection at a diameter of 6 cm. The mechanical substrate for this malignant behavior is …

Microstructure and mechanics of healthy and aneurysmatic abdominal aortas: experimental analysis and modelling

JA Niestrawska, C Viertler… - Journal of The …, 2016 - royalsocietypublishing.org
Soft biological tissues such as aortic walls can be viewed as fibrous composites assembled
by a ground matrix and embedded families of collagen fibres. Changes in the structural …

The role of geometric and biomechanical factors in abdominal aortic aneurysm rupture risk assessment

SS Raut, S Chandra, J Shum, EA Finol - Annals of biomedical engineering, 2013 - Springer
The current clinical management of abdominal aortic aneurysm (AAA) disease is based to a
great extent on measuring the aneurysm maximum diameter to decide when timely …

Fluid-structure interaction in abdominal aortic aneurysms: effects of asymmetry and wall thickness

CM Scotti, AD Shkolnik, SC Muluk, EA Finol - Biomedical engineering …, 2005 - Springer
Background Abdominal aortic aneurysm (AAA) is a prevalent disease which is of significant
concern because of the morbidity associated with the continuing expansion of the …

Hemodynamic influences on abdominal aortic aneurysm disease: Application of biomechanics to aneurysm pathophysiology

MM Dua, RL Dalman - Vascular pharmacology, 2010 - Elsevier
“Atherosclerotic” abdominal aortic aneurysms (AAAs) occur with the greatest frequency in
the distal aorta. The unique hemodynamic environment of this area predisposes it to site …