The N‐acylhydrazone motif has been shown to be particularly adaptable and promising in
the area of medicinal chemistry and drug development, due to its significant biological and …

In this study, a new series of N-acyl hydrazones 7a-e, 8a-e, and 9a-e, starting from methyl δ-
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …

A pair of chemical isomeric structures of N-acylhydrazone compounds I and II were
designed and synthesized. The reaction was carried out with high diastereoselectivity to …

Through a structure-based molecular hybridization strategy, a series of new N-
acylhydrazone derivatives containing the benzothiazole and indole based moiety were …

Hydrazones have versatile properties that make them promising for a range of possible
applications. In this study, we examined a library of 17 aroylhydrazones derived from …

A new series of 8-nitroquinolone-based aromatic heterocyclic acyl hydrazones have been
synthesised and characterised through various spectroscopic techniques. They were …

(Nitrophenyl) hydrazone derivatives of N-acylhydrazone were synthesized and screened for
suppress lymphocyte proliferation and nitrite inhibition in macrophages. Compared to an …

Over the last two decades, N-acylhydrazone (NAH) has been proven to be a very versatile
and promising motif in drug design and medicinal chemistry. Herein, we discuss the current …

Based on the hybrid pharmacophore design concept, a novel series of dual diaryl urea and
N-acylhydrazone derivatives were synthesized and evaluated for their in vitro cytotoxicity by …

Introduction: The N-acylhydrazone (NAH) moiety has been characterized as a privileged
structure, capable of providing ligands points for more than one type of bioreceptor …