Reactive oxygen species are regulated by immune deficiency and Toll pathways in determining the host specificity of honeybee gut bacteria

L Guo, J Tang, M Tang, S Luo… - Proceedings of the …, 2023 - National Acad Sciences
Host specificity is observed in gut symbionts of diverse animal lineages. But how hosts
maintain symbionts while rejecting their close relatives remains elusive. We use eusocial …

Symbionts shape host innate immunity in honeybees

RD Horak, SP Leonard… - Proceedings of the …, 2020 - royalsocietypublishing.org
The gut microbiome plays a critical role in the health of many animals. Honeybees are no
exception, as they host a core microbiome that affects their nutrition and immune function …

Immune system stimulation by the native gut microbiota of honey bees

WK Kwong, AL Mancenido… - Royal Society open …, 2017 - royalsocietypublishing.org
Gut microbial communities can greatly affect host health by modulating the host's immune
system. For many important insects, however, the relationship between the gut microbiota …

Specific Strains of Honeybee Gut Lactobacillus Stimulate Host Immune System to Protect against Pathogenic Hafnia alvei

H Lang, H Duan, J Wang, W Zhang, J Guo… - Microbiology …, 2022 - Am Soc Microbiol
Honeybee gut microbiota plays an important role in host physiology and metabolism. Recent
studies have shown that the influence of the resident microorganisms in the regulation of …

The bacterium Frischella perrara causes scab formation in the gut of its honeybee host

P Engel, KD Bartlett, NA Moran - MBio, 2015 - Am Soc Microbiol
Honeybees harbor well-defined bacterial communities in their guts. The major members of
these communities appear to benefit the host, but little is known about how they interact with …

[HTML][HTML] The innate immune and systemic response in honey bees to a bacterial pathogen, Paenibacillus larvae

QWT Chan, AP Melathopoulos, SF Pernal, LJ Foster - BMC genomics, 2009 - Springer
Background There is a major paradox in our understanding of honey bee immunity: the high
population density in a bee colony implies a high rate of disease transmission among …

[HTML][HTML] The gut microbiota can provide viral tolerance in the honey bee

C Dosch, A Manigk, T Streicher, A Tehel, RJ Paxton… - Microorganisms, 2021 - mdpi.com
Adult honey bees host a remarkably consistent gut microbial community that is thought to
benefit host health and provide protection against parasites and pathogens. Currently …

Honey bee gut dysbiosis: a novel context of disease ecology

KE Anderson, VA Ricigliano - Current opinion in insect science, 2017 - Elsevier
Highlights•Ecological succession of gut bacteria occurs throughout the life of the adult
worker.•Dysbiosis can involve untimely shifts or complete displacement of core …

Functional diversity within the simple gut microbiota of the honey bee

P Engel, VG Martinson… - Proceedings of the …, 2012 - National Acad Sciences
Animals living in social communities typically harbor a characteristic gut microbiota
important for nutrition and pathogen defense. Accordingly, in the gut of the honey bee, Apis …

The gut microbiota protects bees from invasion by a bacterial pathogen

MI Steele, EVS Motta, T Gattu, D Martinez… - Microbiology …, 2021 - Am Soc Microbiol
Commensal microbes in animal guts often help to exclude bacterial pathogens. In honey
bees, perturbing or depleting the gut microbiota increases host mortality rates upon …