The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …

In the last decade, organocatalysis, the use of small chiral organic molecules as catalysts,
has proven to be a valuable and attractive tool for the synthesis of enantiomerically enriched …

The proportion of approved chiral drugs and drug candidates under medical studies has
surged dramatically over the past two decades. As a consequence, the efficient synthesis of …

After an initial period of validating asymmetric organocatalysis by using a wide range of
important model reactions that constitute the essential tools of organic synthesis, the time …

Enantioselective organocatalysis has emerged as a powerful synthetic paradigm that is
complementary to metal-catalysed transformations and has accelerated the development of …

Organocatalysis has emerged as the third pillar of modern asymmetric catalysis in the past
two decades. Applying organocatalytic reactions in total synthesis is currently a highly …

Because the biological and/or pharmacological properties of a given molecule often depend
on the absolute and relative configurations of the stereogenic centers, different …

Conspectus Axially chiral compounds have received much attention from chemists because
of their widespread appearance in natural products, biologically active compounds, and …

Chirality of organic molecules plays an enormous role in areas ranging from medicine to
material science, yet the synthesis of such entities in one enantiomeric form is one of the …

Asymmetric synthesis has become a major aspect of modern organic chemistry. The
stereochemical properties of an organic compound are often essential to its bioactivity, and …