It is well established that different types of exercise can provide a powerful stimulus for
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …

Background While there is agreement that exercise is a powerful stimulus to increase both
mitochondrial function and content, we do not know the optimal training stimulus to …

It has been known for more than 4 decades that exercise causes increases in skeletal
muscle mitochondrial enzyme content and activity (ie, mitochondrial biogenesis). Increasing …

Increased muscle mitochondria are largely responsible for the increased resistance to
fatigue and health benefits ascribed to exercise training. However, very little attention has …

Physical inactivity represents the fourth leading risk factor for mortality, and it has been
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …

Endurance exercise long has been recognized to not only enhance physical performance
but also bring about beneficial health outcomes. The most studied phenotypic adaptations in …

Skeletal muscles require the proper production and distribution of energy to sustain their
work. To ensure this requirement is met, mitochondria form large networks within skeletal …

Mitochondrial biogenesis (ie, the expansion of the mitochondrial reticulum) is one of the
most well-established adaptations to exercise training in skeletal muscle. Since the first in …

Mitochondrial health is an important mediator of cellular function across a range of tissues,
and as a result contributes to whole‐body vitality in health and disease. Our understanding …

Mitochondrial dysfunction is a crucial contributor to heart diseases. Alterations in energetic
metabolism affect crucial homeostatic processes, such asATP production, the generation of …