An Insight Into the Modulatory Effects and Mechanisms of Action of Phyllanthus Species and Their Bioactive Metabolites on the Immune System

I Jantan, MA Haque, M Ilangkovan… - Frontiers in …, 2019 - frontiersin.org
Phyllanthus species (family; Euphorbiaceae) have been intensively studied for their
immunomodulating effects due to their wide-ranging uses to treat immune-related diseases …

In vitro and in vivo anti-inflammatory activity of Phyllanthus acidus methanolic extract

MJ Hossen, SH Jeon, SC Kim, JH Kim, D Jeong… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Phyllanthus acidus (L.) Skeels (Phyllanthaceae) has
traditionally been used to treat gastric trouble, rheumatism, bronchitis, asthma, respiratory …

Modulation of cell signaling pathways by Phyllanthus amarus and its major constituents: potential role in the prevention and treatment of inflammation and cancer

H Harikrishnan, I Jantan, A Alagan, MA Haque - Inflammopharmacology, 2020 - Springer
The causal and functional connection between inflammation and cancer has become a
subject of much research interest. Modulation of cell signaling pathways, such as those …

Anti-oxidant and inflammatory mediator's growth inhibitory effects of compounds isolated from Phyllanthus urinaria

SH Fang, YK Rao, YM Tzeng - Journal of Ethnopharmacology, 2008 - Elsevier
Phyllanthus urinaria Linnea (Euphorbiaceae), is a traditional anti-hepatitis herb used in
Taiwan. In continuation of our search for potent natural anti-inflammatory agents, from the …

Immuno-enhancement effects of Platycodon grandiflorum extracts in splenocytes and a cyclophosphamide-induced immunosuppressed rat model

EM Noh, JM Kim, HY Lee, HK Song, SO Joung… - … and Alternative Medicine, 2019 - Springer
Background Platycodon grandiflorum is a flowering plant that is used in traditional medicine
for treating pulmonary and respiratory disorders. It exerts various pharmacological effects …

Anti-inflammatory effects of Phyllanthus amarus Schum. & Thonn. through inhibition of NF-κB, MAPK, and PI3K-Akt signaling pathways in LPS-induced human …

H Harikrishnan, I Jantan, MA Haque… - BMC complementary and …, 2018 - Springer
Background Phyllanthus amarus has been used widely in various traditional medicines to
treat swelling, sores, jaundice, inflammatory diseases, kidney disorders, diabetes and viral …

Chemical Components and Biological Activities of the Genus Phyllanthus: A Review of the Recent Literature

MF Nisar, J He, A Ahmed, Y Yang, M Li, C Wan - Molecules, 2018 - mdpi.com
Medicinal plants have served humans since prehistoric times to treat various ailments. Both
developed and underdeveloped countries rely on traditional systems of medication using …

Immunomodulatory effects and mechanisms of the extracts and secondary compounds of Zingiber and Alpinia species: a review

Yuandani, I Jantan, MA Haque, AS Rohani… - Frontiers in …, 2023 - frontiersin.org
Zingiber and Alpinia species (family: Zingiberaceae) are popularly used in food as spices
and flavoring agents and in ethnomedicine to heal numerous diseases, including immune …

Phyllanthus emblica: a comprehensive review of its phytochemical composition and pharmacological properties

AT Prananda, A Dalimunthe, U Harahap… - Frontiers in …, 2023 - frontiersin.org
Phyllanthus emblica Linn, a prominent member of the euphorbiaceae family, exhibits
extensive distribution across a multitude of tropical and subtropical nations. Referred to as …

Phyllanthus acidus (L.) Skeels: A review of its traditional uses, phytochemistry, and pharmacological properties

SP Tan, ENY Tan, QY Lim, MA Nafiah - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Phyllanthus acidus (L.) Skeels is not only used for its
edible fruits but also used to treat a wide spectrum of diseases such as inflammatory …