The genetic basis for the fine-tuned regulation of gene expression is complex and ultimately
influences the phenotype and thus the local adaptation of natural populations. Short tandem …

Short tandem repeat (STR) mutations may comprise more than half of the mutations in
eukaryotic coding DNA, yet STR variation is rarely examined as a contributor to complex …

Short tandem repeats (STRs) are hypervariable genetic elements that occur frequently in
coding regions. Their high mutation rate readily generates genetic variation, contributing to …

Genome-wide simple sequence repeat (SSR) information was analyzed together with
functional annotations of Arabidopsis genes and public gene expression data for …

Eukaryotic genomes are mostly composed of noncoding DNA whose role is still poorly
understood. Studies in several organisms have shown correlations between the length of …

A fundamental question in biology is how gene expression is regulated to give rise to a
phenotype. However, transcriptional variability is rarely considered although it could …

Simple sequence repeats (SSRs) are a group of repetitive DNA sequences that represent a
significant portion of higher eukaryote genomes. They can serve as highly informative …

Abstract Background Simple sequence repeats (SSRs) in DNA have been traditionally
thought of as functionally unimportant and have been studied mainly as genetic markers. A …

The advances of high-throughput sequencing offer an unprecedented opportunity to study
genetic variation. This is challenged by the difficulty of resolving variant calls in repetitive …

Efforts to identify loci underlying complex traits generally assume that most genetic variance
is additive. Here, we examined the genetics of Arabidopsis thaliana root length and found …