Objective—Apolipoprotein E (apoE) exerts potent antiinflammatory effects. Here, we
investigated the effect of apoE on the functional phenotype of macrophages. Methods and …

Apolipoprotein E (apoE) is synthesized in the liver and in macrophages, and it has
antiatherogenic properties that are mediated, at least in part, through the regulation of …

Objective—We investigated atheroprotective properties of apolipoprotein (apo) E beyond its
ability to lower plasma cholesterol. We hypothesized that apoE reduces atherosclerosis by …

Apolipoprotein E (apoE) is a multifunctional glycosylated protein characterized by its wide
tissue distribution. Despite its importance in lipid transport and atherosclerosis …

In order to gain a more comprehensive understanding of the aetiology of apolipoprotein E4
genotype-cardiovascular disease (CVD) associations, the impact of the apoE genotype on …

Apolipoprotein E (apoE) is a 34-kDa glycoprotein involved in lipoprotein transport through
interaction with the low-density lipoprotein receptor and related receptors. Recently, it has …

Apolipoprotein E (apoE) is a 34 kDa glycosylated protein with multiple biological properties.
In addition to its role in cholesterol transport, apoE has in vitro immunomodulatory …

Rationale: Apolipoprotein E (apoE) exerts anti-inflammatory properties that protect against
atherosclerosis and other inflammatory diseases. However, mechanisms by which apoE …

Apolipoprotein (apo) E4 is a major genetic risk factor for a wide spectrum of inflammatory
metabolic diseases, including atherosclerosis, diabetes, and Alzheimer disease. This study …

Human apolipoprotein E is the major apolipoprotein expressed in the brain and exists as
three isoforms, designated E2, E3, and E4. Although evidence suggests that apolipoprotein …