Neurological disorders leading to mechanical dysfunction of the esophagus: an emergent behavior of a neuromechanical dynamical system

G Elisha, S Halder, X Liu, DA Carlson… - arXiv preprint arXiv …, 2024 - arxiv.org
An understanding how neurological disorders lead to mechanical dysfunction of the
esophagus requires knowledge of the neural circuit of the enteric nervous system …

Characterization of esophageal physiology using mechanical state analysis

RE Leibbrandt, PG Dinning, M Costa… - Frontiers in systems …, 2016 - frontiersin.org
The esophagus functions to transport swallowed fluids and food from the pharynx to the
stomach. The esophageal muscles governing bolus transport comprise circular striated …

Neural regulation of slow waves and phasic contractions in the distal stomach: a mathematical model

ON Athavale, R Avci, AR Clark… - Journal of Neural …, 2024 - iopscience.iop.org
Objective. Neural regulation of gastric motility occurs partly through the regulation of gastric
bioelectrical slow waves (SWs) and phasic contractions. The interaction of the tissues and …

Mechanosensitivity in the enteric nervous system

G Mazzuoli-Weber, M Schemann - Frontiers in cellular neuroscience, 2015 - frontiersin.org
The enteric nervous system (ENS) autonomously controls gut muscle activity.
Mechanosensitive enteric neurons (MEN) initiate reflex activity by responding to mechanical …

Esophageal motor disorders: recent advances

I Dogan, RK Mittal - Current opinion in gastroenterology, 2006 - journals.lww.com
Several novel techniques, perfected during recent years, have improved our understanding
of esophageal function and dysfunction. A number of important observations, reviewed here …

The “simultaneous contractions” of the human colon are a fast propagating rhythmic neurogenic motor pattern associated internal anal sphincter relaxation and gas …

JH Chen, Y Yu, Z Yang, WZ Yu… - Autonomic …, 2015 - autonomicneuroscience.com
Background. Colonic contractile patterns are the result of the interplay of spontaneous
pacemaker currents and the enteric nervous system (ENS). Aim. To describe the motility …

Neural signalling of gut mechanosensation in ingestive and digestive processes

M Kim, G Heo, SY Kim - Nature Reviews Neuroscience, 2022 - nature.com
Eating and drinking generate sequential mechanosensory signals along the digestive tract.
These signals are communicated to the brain for the timely initiation and regulation of …

Neural regulatory mechanisms of esophageal motility and its implication for GERD

T Shiina, Y Shimizu - Gastroesophageal Reflux Disease, 2012 - books.google.com
Gastroesophageal reflux disease (GERD) is one of the representative esophageal disorders
and can severely influence the quality of life in humans (Jung, 2011; Moayyedi & Talley …

Engaging biological oscillators through second messenger pathways permits emergence of a robust gastric slow-wave during peristalsis

MA Ahmed, S Venugopal, R Jung - PLoS Computational Biology, 2021 - journals.plos.org
Peristalsis, the coordinated contraction—relaxation of the muscles of the stomach is
important for normal gastric motility and is impaired in motility disorders. Coordinated …

Gastric motility

A Sanjeevi - Current opinion in gastroenterology, 2007 - journals.lww.com
Using dynamic imaging modalities, the pathophysiology of dyspepsia is becoming better
understood and recognized as an end point of multifactorial dysfunction of the enteric neural …