[HTML][HTML] Nose-to-brain delivery of therapeutic peptides as nasal aerosols
Central nervous system (CNS) disorders, such as psychiatric disorders, neurodegeneration,
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …
Drug development of intranasally delivered peptides
C Campbell, BH Morimoto, D Nenciu… - Therapeutic delivery, 2012 - Future Science
Intranasal drug delivery has attracted increasing attention as a noninvasive route of
administration for therapeutic proteins and peptides. The delivery of therapeutic peptides …
administration for therapeutic proteins and peptides. The delivery of therapeutic peptides …
Nasal drug delivery: new developments and strategies
L Illum - Drug discovery today, 2002 - Elsevier
The use of the nasal route for the delivery of challenging drugs has created much interest in
recent years in the pharmaceutical industry. Consequently, drug delivery companies are …
recent years in the pharmaceutical industry. Consequently, drug delivery companies are …
Overview of intranasally delivered peptides: key considerations for pharmaceutical development
W Al Bakri, MD Donovan, M Cueto, Y Wu… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Intranasal (IN) delivery for peptides provides unique advantages compared to
other invasive systemic delivery routes. However, there still lacks a clear understanding on …
other invasive systemic delivery routes. However, there still lacks a clear understanding on …
Formulation and physiological factors influencing CNS delivery upon intranasal administration
The treatment of central nervous system (CNS) disorders is particularly challenging because
of a variety of formidable barriers to effective and persistent delivery of therapeutic …
of a variety of formidable barriers to effective and persistent delivery of therapeutic …
[HTML][HTML] Cell-Penetrating Peptides as Valuable Tools for Nose-to-Brain Delivery of Biological Drugs
LB De Martini, C Sulmona, L Brambilla, D Rossi - Cells, 2023 - mdpi.com
Due to their high specificity toward the target and their low toxicity, biological drugs have
been successfully employed in a wide range of therapeutic areas. It is yet to be mentioned …
been successfully employed in a wide range of therapeutic areas. It is yet to be mentioned …
Intranasal drug delivery
AA Hussain - Advanced Drug Delivery Reviews, 1998 - Elsevier
In recent years the nasal route has received a great deal of attention as a convenient and
reliable method for the systemic administration of drugs. Although this route is currently …
reliable method for the systemic administration of drugs. Although this route is currently …
Advances in nasal trans-mucosal drug delivery
SKS Kushwaha, RK Keshari, AK Rai - Journal of applied …, 2011 - japsonline.com
Transmucosal nasal delivery is a promising drug delivery option where common drug
administrations, such as intravenous, intramuscular, or oral are inapplicable. Recently, it has …
administrations, such as intravenous, intramuscular, or oral are inapplicable. Recently, it has …
Delivery of peptide and non-peptide drugs through the respiratory tract
SS Davis - Pharmaceutical science & technology today, 1999 - Elsevier
The respiratory tract, and the nose in particular, offers opportunities for improved drug
delivery. Many drugs are rapidly and efficiently absorbed from the nasal cavity and, as a …
delivery. Many drugs are rapidly and efficiently absorbed from the nasal cavity and, as a …
Intranasal drug delivery system-A glimpse to become maestro
S Upadhyay, A Parikh, P Joshi… - Journal of applied …, 2011 - japsonline.com
Intranasal drug delivery–which has been practiced for thousands of years, has been given a
new lease of life. It is a useful delivery method for drugs that are active in low doses and …
new lease of life. It is a useful delivery method for drugs that are active in low doses and …