[HTML][HTML] Nose-to-brain delivery of therapeutic peptides as nasal aerosols

W Alabsi, BB Eedara, D Encinas-Basurto, R Polt… - Pharmaceutics, 2022 - mdpi.com
Central nervous system (CNS) disorders, such as psychiatric disorders, neurodegeneration,
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …

Drug development of intranasally delivered peptides

C Campbell, BH Morimoto, D Nenciu… - Therapeutic delivery, 2012 - Future Science
Intranasal drug delivery has attracted increasing attention as a noninvasive route of
administration for therapeutic proteins and peptides. The delivery of therapeutic peptides …

Nasal drug delivery: new developments and strategies

L Illum - Drug discovery today, 2002 - Elsevier
The use of the nasal route for the delivery of challenging drugs has created much interest in
recent years in the pharmaceutical industry. Consequently, drug delivery companies are …

Overview of intranasally delivered peptides: key considerations for pharmaceutical development

W Al Bakri, MD Donovan, M Cueto, Y Wu… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Intranasal (IN) delivery for peptides provides unique advantages compared to
other invasive systemic delivery routes. However, there still lacks a clear understanding on …

Formulation and physiological factors influencing CNS delivery upon intranasal administration

T Vyas, SB Tiwari, MM Amiji - Critical Reviews™ in Therapeutic …, 2006 - dl.begellhouse.com
The treatment of central nervous system (CNS) disorders is particularly challenging because
of a variety of formidable barriers to effective and persistent delivery of therapeutic …

[HTML][HTML] Cell-Penetrating Peptides as Valuable Tools for Nose-to-Brain Delivery of Biological Drugs

LB De Martini, C Sulmona, L Brambilla, D Rossi - Cells, 2023 - mdpi.com
Due to their high specificity toward the target and their low toxicity, biological drugs have
been successfully employed in a wide range of therapeutic areas. It is yet to be mentioned …

Intranasal drug delivery

AA Hussain - Advanced Drug Delivery Reviews, 1998 - Elsevier
In recent years the nasal route has received a great deal of attention as a convenient and
reliable method for the systemic administration of drugs. Although this route is currently …

Advances in nasal trans-mucosal drug delivery

SKS Kushwaha, RK Keshari, AK Rai - Journal of applied …, 2011 - japsonline.com
Transmucosal nasal delivery is a promising drug delivery option where common drug
administrations, such as intravenous, intramuscular, or oral are inapplicable. Recently, it has …

Delivery of peptide and non-peptide drugs through the respiratory tract

SS Davis - Pharmaceutical science & technology today, 1999 - Elsevier
The respiratory tract, and the nose in particular, offers opportunities for improved drug
delivery. Many drugs are rapidly and efficiently absorbed from the nasal cavity and, as a …

Intranasal drug delivery system-A glimpse to become maestro

S Upadhyay, A Parikh, P Joshi… - Journal of applied …, 2011 - japsonline.com
Intranasal drug delivery–which has been practiced for thousands of years, has been given a
new lease of life. It is a useful delivery method for drugs that are active in low doses and …