Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis

SC Eames, LH Philipson, VE Prince, MD Kinkel - Zebrafish, 2010 - liebertpub.com
The adult zebrafish has the potential to become an important model for diabetes-related
research. To realize this potential, small-scale methods for analyzing pancreas function are …

A novel, reliable method for repeated blood collection from aquarium fish

L Zang, Y Shimada, Y Nishimura, T Tanaka… - Zebrafish, 2013 - liebertpub.com
Collecting blood from laboratory animals is necessary for a wide variety of scientific studies,
but the small size of the zebrafish makes this common procedure challenging. We …

Sweet fish: Fish models for the study of hyperglycemia and diabetes

J Krishnan, N Rohner - Journal of diabetes, 2019 - Wiley Online Library
Fish are good for your health in more ways than you may expect. For one, eating fish is a
common dietary recommendation for a healthy diet. However, fish have much more to …

Development of a novel zebrafish model for type 2 diabetes mellitus

L Zang, Y Shimada, N Nishimura - Scientific reports, 2017 - nature.com
Obesity is a major cause of type 2 diabetes mellitus (T2DM) in mammals. We have
previously established a zebrafish model of diet-induced obesity (DIO zebrafish) by …

Zebrafish as a model for obesity and diabetes

L Zang, LA Maddison, W Chen - Frontiers in cell and developmental …, 2018 - frontiersin.org
Obesity and diabetes now considered global epidemics. The prevalence rates of diabetes
are increasing in parallel with the rates of obesity and the strong connection between these …

Repeated blood collection for blood tests in adult zebrafish

L Zang, Y Shimada, Y Nishimura, T Tanaka… - JoVE (Journal of …, 2015 - jove.com
Repeated blood collection is one of the most common techniques performed on laboratory
animals. However, a non-lethal protocol for blood collection from zebrafish has not been …

Blood collection for biochemical analysis in adult zebrafish

GL Pedroso, TO Hammes, TDC Escobar… - JoVE (Journal of …, 2012 - jove.com
The zebrafish has been used as an animal model for studies of several human diseases. It
can serve as a powerful preclinical platform for studies of molecular events and therapeutic …

Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age-and diet-dependent manner

LA Maddison, KE Joest… - American Journal of …, 2015 - journals.physiology.org
Insulin resistance creates an environment that promotes β-cell failure and development of
diabetes. Understanding the events that lead from insulin resistance to diabetes is …

Glucose metabolism and gene expression in juvenile zebrafish (Danio rerio) challenged with a high carbohydrate diet: effects of an acute glucose stimulus during late …

F Rocha, J Dias, S Engrola, P Gavaia… - British Journal of …, 2015 - cambridge.org
Knowledge on the role of early nutritional stimuli as triggers of metabolic pathways in fish is
extremely scarce. The objective of the present study was to assess the long-term effects of …

Glucose determination in fish plasma by two different moderate methods

J Bartoňková, P Hyršl, L Vojtek - Acta Veterinaria Brno, 2017 - actavet.vfu.cz
Teleost fish include many different species, having a large economic and environmental
impact. Glucose is a key source of energy for most vertebrate organisms. Fish as well as …