IMPLICATIONS: The present study demonstrates that sevoflurane can dose-dependently
inhibit both angiotensin II (Ang II)-induced contraction and p44/42 MAPK phosphorylation of …

Background Whether volatile anesthetics attenuate angiotensin II-mediated vascular tone
has not been determined. The current study was designed to investigate the effects of …

BACKGROUND: Angiotensin II (Ang II)-induced vascular contraction is mediated both by a
Ca 2+-mediated signaling pathway and a Ca 2+ sensitization mechanism. We recently …

Abstract Purpose Angiotensin II (Ang II)-induced vasoconstriction is mediated by changes in
intracellular free Ca 2+ concentration ([Ca 2+] i) and myofilament Ca 2+ sensitivity. Protein …

Background Tyrosine kinase-catalyzed protein tyrosine phosphorylation plays an important
role in initiating and modulating vascular smooth muscle contraction. The aim of the current …

Abstract Purpose Angiotensin II (Ang II)-induced vascular contraction is mediated by Ca 2+-
dependent mechanisms and Ca 2+ sensitization mechanisms. The phosphorylation of …

Background: Isoflurane induces greater effects on vasodilation and decreasing blood
pressure than sevoflurane. Tyrosine kinase‐catalyzed protein tyrosine phosphorylation …

Background Angiotensin II (AngII) is a potent vasoconstrictor involved in the short-term
control of arterial blood pressure. Isoflurane was reported to decrease vascular tone through …

Background Class II phosphoinositide 3-kinase α-isoform (PI3K-C2α) is involved in
regulating KCl-induced vascular smooth muscle contraction. The current study was to …

Background Although halothane and isoflurane inhibit receptor agonist-induced smooth
muscle contraction by inhibiting Ca2+ influx via the L-type voltage-dependent Ca2+ …