Ischaemic stroke causes neuron loss and long-term functional deficits. Unfortunately,
effective approaches to preserving neurons and promoting functional recovery remain …

Brain tissue undergoes substantial activity-dependent reorganisation after stroke due to
neuronal plasticity, leading to partial functional recovery in patients. Concurrent myelin …

Stroke is a major reason for persistent disability due to insufficient treatment strategies
beyond reperfusion, leading to oligodendrocyte death and axon demyelination, persistent …

Functional implication for myelin regeneration in recovery from ischaemic stroke | Brain | Oxford
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White matter damage is a clinically important aspect of several central nervous system
diseases, including stroke. Cerebral white matter primarily consists of axonal bundles …

Ischemic stroke is a neurological disorder representing a leading cause of death and
permanent disability world-wide, for which effective regenerative treatments are missing …

Demyelination occurs in response to brain injury and is observed in many
neurodegenerative diseases. Myelin is synthesized from oligodendrocytes in the central …

Brain ischemia, also known as ischemic stroke, occurs when there is a lack of blood supply
into the brain. When an ischemic insult appears, both neurons and glial cells can react in …

Background and Purpose—Axonal remodeling is critical to brain repair after stroke. The
present study investigated axonal outgrowth after stroke and the signaling pathways …

Damage to myelinated axons contributes to neurological deficits after acute CNS injury,
including ischemic and hemorrhagic stroke. Potential treatments to promote re-myelination …