[HTML][HTML] Emerging promise of therapeutic approaches targeting mitochondria in neurodegenerative disorders

MM Rahman, MAA Tumpa, MS Rahaman… - Current …, 2023 - ncbi.nlm.nih.gov
Mitochondria are critical for homeostasis and metabolism in all cellular eukaryotes. Brain
mitochondria are the primary source of fuel that supports many brain functions, including …

The failure of mitochondria leads to neurodegeneration: Do mitochondria need a jump start?

J Lee, JH Boo, H Ryu - Advanced drug delivery reviews, 2009 - Elsevier
Mitochondria are the power engine generating biochemical energy in the cell. Mitochondrial
dysfunction and bioenergy deficiency is closely linked to the pathogenesis of …

Mitochondrial medicine for neurodegenerative diseases

H Du, SSD Yan - The international journal of biochemistry & cell biology, 2010 - Elsevier
Mitochondrial dysfunction has been reported in a wide array of neurological disorders
ranging from neuromuscular to neurodegenerative diseases. Recent studies on …

[HTML][HTML] Mitochondrial dysfunction in neurodegenerative disorders

MM Klemmensen, SH Borrowman, C Pearce, B Pyles… - …, 2023 - Elsevier
Recent advances in understanding the role of mitochondrial dysfunction in
neurodegenerative diseases have expanded the opportunities for neurotherapeutics …

Mitochondrial medicine and the neurodegenerative mitochondriopathies

RH Swerdlow - Pharmaceuticals, 2009 - mdpi.com
Neurodegenerative diseases are a common late-life scourge for which disease-modifying
treatments are sorely needed. Mitochondrial perturbation is commonly observed in these …

Mitochondrial Dysfunction as a Signaling Target for Therapeutic Intervention in Major Neurodegenerative Disease

SV Mangrulkar, NL Wankhede, MB Kale… - Neurotoxicity …, 2023 - Springer
Neurodegenerative diseases (NDD) are incurable and the most prevalent cognitive and
motor disorders of elderly. Mitochondria are essential for a wide range of cellular processes …

Targeting mitochondria in the regulation of neurodegenerative diseases: A comprehensive review

SK Maurya, S Gupta, A Bakshi, H Kaur… - Journal of …, 2022 - Wiley Online Library
Mitochondria are one of the essential cellular organelles. Apart from being considered as
the powerhouse of the cell, mitochondria have been widely known to regulate redox …

[HTML][HTML] Mitochondrial medicine: A promising therapeutic option against various neurodegenerative disorders

MA Almikhlafi, MM Karami, A Jana… - Current …, 2023 - ncbi.nlm.nih.gov
Abnormal mitochondrial morphology and metabolic dysfunction have been observed in
many neurodegenerative disorders (NDDs). Mitochondrial dysfunction can be caused by …

Novel therapeutic strategies targeting mitochondria as a gateway in neurodegeneration

D Trigo, JJ Vitória, OABC e Silva - Neural Regeneration Research, 2023 - journals.lww.com
In recent years, multiple disciplines have focused on mitochondrial biology and contributed
to understanding its relevance towards adult-onset neurodegenerative disorders. These are …

[PDF][PDF] Mitochondrial Medicine for Neurological Disorders

MS Uddin, BS Alghamdi… - Current …, 2023 - scienceopen.com
Mitochondrial dysfunction is a vital aspect of copious neurological ailments ranging from
neuromuscular to neurodegenerative diseases. Mitochondrial dysfunction in the form of …