The roles of glucose metabolic reprogramming in chemo-and radio-resistance
J Lin, L Xia, J Liang, Y Han, H Wang, L Oyang… - Journal of Experimental …, 2019 - Springer
Reprogramming of cancer metabolism is a newly recognized hallmark of malignancy. The
aberrant glucose metabolism is associated with dramatically increased bioenergetics …
aberrant glucose metabolism is associated with dramatically increased bioenergetics …
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
N Hay - Nature Reviews Cancer, 2016 - nature.com
In recent years there has been a growing interest among cancer biologists in cancer
metabolism. This Review summarizes past and recent advances in our understanding of the …
metabolism. This Review summarizes past and recent advances in our understanding of the …
Glycogen metabolism has a key role in the cancer microenvironment and provides new targets for cancer therapy
CE Zois, AL Harris - Journal of molecular medicine, 2016 - Springer
Metabolic reprogramming is a hallmark of cancer cells and contributes to their adaption
within the tumour microenvironment and resistance to anticancer therapies. Recently …
within the tumour microenvironment and resistance to anticancer therapies. Recently …
Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression
Z Li, H Zhang - Cellular and molecular life sciences, 2016 - Springer
Metabolic reprogramming is widely observed during cancer development to confer cancer
cells the ability to survive and proliferate, even under the stressed, such as nutrient-limiting …
cells the ability to survive and proliferate, even under the stressed, such as nutrient-limiting …
Glucose metabolism on tumor plasticity, diagnosis, and treatment
X Lin, Z Xiao, T Chen, SH Liang, H Guo - Frontiers in oncology, 2020 - frontiersin.org
Malignant cells support tumor proliferation and progression by adopting to metabolic
changes. Tumor cells altered metabolism by increasing glucose uptake and fermentation of …
changes. Tumor cells altered metabolism by increasing glucose uptake and fermentation of …
Modulating glycolysis to improve cancer therapy
Cancer cells undergo metabolic reprogramming and switch to a 'glycolysis-
dominant'metabolic profile to promote their survival and meet their requirements for energy …
dominant'metabolic profile to promote their survival and meet their requirements for energy …
Targeting glucose metabolism for cancer therapy
RB Hamanaka, NS Chandel - Journal of Experimental Medicine, 2012 - rupress.org
Cellular transformation is associated with the reprogramming of cellular pathways that
control proliferation, survival, and metabolism. Among the metabolic changes exhibited by …
control proliferation, survival, and metabolism. Among the metabolic changes exhibited by …
Glucose addiction in cancer therapy: advances and drawbacks
While normal differentiated cells primarily use mitochondrial respiration to generate the
required energy for cellular processes, most cancer cells rely on glycolysis, even in sufficient …
required energy for cellular processes, most cancer cells rely on glycolysis, even in sufficient …
Altered glycolysis results in drug‑resistant in clinical tumor therapy
Cancer cells undergo metabolic reprogramming, including increased glucose metabolism,
fatty acid synthesis and glutamine metabolic rates. These enhancements to three major …
fatty acid synthesis and glutamine metabolic rates. These enhancements to three major …
Targeting cancer metabolism to resensitize chemotherapy: potential development of cancer chemosensitizers from traditional Chinese medicines
Cancer is a common and complex disease with high incidence and mortality rates, which
causes a severe public health problem worldwide. As one of the standard therapeutic …
causes a severe public health problem worldwide. As one of the standard therapeutic …