Vascular‐targeted nanocarriers: design considerations and strategies for successful treatment of atherosclerosis and other vascular diseases

WJ Kelley, H Safari, G Lopez‐Cazares… - Wiley …, 2016 - Wiley Online Library
Vascular‐targeted nanocarriers are an attractive option for the treatment of a number of
cardiovascular diseases, as they allow for more specific delivery and increased efficacy of …

Nanomedicine approaches in vascular disease: a review

AS Gupta - Nanomedicine: Nanotechnology, Biology and Medicine, 2011 - Elsevier
Nanomedicine approaches have revolutionized the treatment of cancer and vascular
diseases, where the limitations of rapid nonspecific clearance, poor biodistribution and …

Targeted therapeutics and nanodevices for vascular drug delivery: Quo vadis?

VR Muzykantov - IUBMB life, 2011 - Wiley Online Library
This issue of the journal is dedicated to targeted delivery of therapeutics in the vasculature,
an approach that holds promise to optimize treatment of diverse pathological conditions …

Nature-inspired nanocarriers for improving drug therapy of atherosclerosis

W Ji, Y Zhang, Y Deng, C Li… - Regenerative …, 2023 - academic.oup.com
Atherosclerosis (AS) has emerged as one of the prevalent arterial vascular diseases
characterized by plaque and inflammation, primarily causing disability and mortality globally …

[HTML][HTML] Nanomedicine-based drug delivery strategies for the treatment of atherosclerosis

Y Lin, R Lin, HB Lin, S Shen - Medicine in Drug Discovery, 2024 - Elsevier
Atherosclerosis, a highly prevalent cardiovascular disease, has significantly contributed to
morbidity and mortality worldwide. Despite the availability of various treatment options in …

Vascular targeting of nanocarriers: perplexing aspects of the seemingly straightforward paradigm

M Howard, BJ Zern, AC Anselmo, VV Shuvaev… - ACS …, 2014 - ACS Publications
Targeted nanomedicine holds promise to find clinical use in many medical areas.
Endothelial cells that line the luminal surface of blood vessels represent a key target for …

Nano-systems for advanced therapeutics and diagnosis of atherosclerosis

C Gaurav, B Saurav, R Goutam… - Current Pharmaceutical …, 2015 - ingentaconnect.com
Cardiovascular diseases (CVDs) are the leading cause of death and morbidity worldwide.
Atherosclerotic situations such as acute myocardial infarction (MI) and stroke are still major …

[HTML][HTML] Biomimetic nanomedicines for precise atherosclerosis theranostics

Y Tao, X Lan, Y Zhang, C Fu, L Liu, F Cao… - … Pharmaceutica Sinica B, 2023 - Elsevier
Atherosclerosis (AS) is a leading cause of the life-threatening cardiovascular disease (CVD),
creating an urgent need for efficient, biocompatible therapeutics for diagnosis and treatment …

Surface-modified nanotherapeutics targeting atherosclerosis

W Li, KM Gonzalez, J Chung, M Kim, J Lu - Biomaterials science, 2022 - pubs.rsc.org
Atherosclerosis is a chronic and metabolic-related disease that is a serious threat to human
health. Currently available diagnostic and therapeutic measures for atherosclerosis lack …

Collaborative enhancement of endothelial targeting of nanocarriers by modulating platelet-endothelial cell adhesion molecule-1/CD31 epitope engagement

AM Chacko, J Han, CF Greineder, BJ Zern, JL Mikitsh… - ACS …, 2015 - ACS Publications
Nanocarriers (NCs) coated with antibodies (Abs) to extracellular epitopes of the
transmembrane glycoprotein PECAM (platelet endothelial cell adhesion molecule-1/CD31) …