Clonal evolution analysis of paired anaplastic and well‐differentiated thyroid carcinomas reveals shared common ancestor

W Dong, NG Nicolson, J Choi… - Genes …, 2018 - Wiley Online Library
Foci of papillary or follicular thyroid carcinoma are frequently noted in thyroidectomy
specimens of anaplastic thyroid carcinoma (ATC). However, whether ATCs evolve from …

[HTML][HTML] Early evolutionary divergence between papillary and anaplastic thyroid cancers

J Capdevila, R Mayor, FM Mancuso, C Iglesias… - Annals of …, 2018 - Elsevier
Background Papillary thyroid cancer (PTC) is the most common thyroid carcinoma and
exhibits an almost uniformly good prognosis, while anaplastic thyroid cancer (ATC) is less …

[HTML][HTML] Not the same thing: metastatic PTCs have a different background than ATCs

D de Biase, F Torricelli, M Ragazzi… - Endocrine …, 2018 - ec.bioscientifica.com
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive form of thyroid cancer. By
contrast, differentiated papillary thyroid cancer (PTC) only rarely behave aggressively and …

[PDF][PDF] The genomic and evolutionary landscapes of anaplastic thyroid carcinoma

PYF Zeng, SD Prokopec, SY Lai, N Pinto… - Cell Reports, 2024 - cell.com
Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-
occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are …

Anaplastic thyroid cancer: cytogenetic patterns by comparative genomic hybridization

D Miura, N Wada, K Chin, GG Magrane, M Wong… - Thyroid, 2003 - liebertpub.com
We studied chromosomal abnormalities by comparative genomic hybridization (CGH) and
flow cytometry in anaplastic thyroid cancer (ATC), and when present in coexisting or …

Unique mutation patterns in anaplastic thyroid cancer identified by comprehensive genomic profiling

SA Khan, B Ci, Y Xie, DE Gerber, MS Beg… - Head & …, 2019 - Wiley Online Library
Introduction Anaplastic thyroid cancer (ATC) is a highly aggressive thyroid cancer. Those
ATC with genomic alterations (GAs) in TSC2, ALK, and BRAF may respond to targeted …

[HTML][HTML] Identification of targetable lesions in anaplastic thyroid cancer by genome profiling

N Ravi, M Yang, S Gretarsson, C Jansson, N Mylona… - Cancers, 2019 - mdpi.com
Anaplastic thyroid cancer (ATC) is a rare and extremely malignant tumor with no available
cure. The genetic landscape of this malignancy has not yet been fully explored. In this study …

Primary versus secondary anaplastic thyroid carcinoma: perspectives from multi-institutional and population-level data

TNM Ngo, TTB Le, T Le, A Bychkov, N Oishi… - Endocrine …, 2021 - Springer
Primary (or de novo) anaplastic thyroid carcinoma (ATC) is ATC without pre-existing history
of differentiated thyroid carcinoma (DTC) and no co-existing DTC foci at the time of …

Coexisting well-differentiated and anaplastic thyroid carcinoma in the same primary resection specimen: immunophenotypic and genetic comparison of the two …

M Ragazzi, F Torricelli, B Donati, A Ciarrocchi… - Virchows Archiv, 2021 - Springer
Anaplastic carcinoma (AC) is a rare but highly aggressive form of thyroid cancer. It mostly
arises on a background of pre-existing well-differentiated cancer (WDC); however, whether it …

[HTML][HTML] Poorly differentiated and anaplastic thyroid carcinomas: chromosomal and oligo-array profile of five new cell lines

RF Rodrigues, L Roque, T Krug, V Leite - British journal of cancer, 2007 - nature.com
Abstract Information on gene alterations associated to poorly differentiated (PDTC) and
anaplastic thyroid carcinomas (ATC) is scarce. Using human cancer cell lines as a tool for …