[HTML][HTML] The gut microbiota, HPA axis, and brain in adolescent-onset depression: Probiotics as a novel treatment

D Freimer, TT Yang, TC Ho, O Tymofiyeva… - Brain, Behavior, & …, 2022 - Elsevier
Stress-associated disruptions in the development of frontolimbic regions may play a critical
role in the emergence of adolescent-onset depression. These regions are particularly …

Probiotics for the treatment of depressive symptoms: an anti-inflammatory mechanism?

C Park, E Brietzke, JD Rosenblat, N Musial… - Brain, Behavior, and …, 2018 - Elsevier
During the past decade, there has been renewed interest in the relationship between brain-
based disorders, the gut microbiota, and the possible beneficial effects of probiotics …

Prebiotic and probiotic modulation of the microbiota–gut–brain axis in depression

DE Radford-Smith, DC Anthony - Nutrients, 2023 - mdpi.com
Emerging evidence demonstrates that alterations to the gut microbiota can affect mood,
suggesting that the microbiota–gut–brain (MGB) axis contributes to the pathogenesis of …

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials

M Pirbaglou, J Katz, RJ de Souza, JC Stearns… - Nutrition research, 2016 - Elsevier
Gastrointestinal microbiota, consisting of microbial communities in the gastrointestinal tract,
play an important role in digestive, metabolic, and immune functioning. Preclinical studies …

Gut emotions-mechanisms of action of probiotics as novel therapeutic targets for depression and anxiety disorders

A Slyepchenko, AF Carvalho, DS Cha… - CNS & Neurological …, 2014 - ingentaconnect.com
A priority clinical and research agenda in mood and anxiety disorders is to identify
determinants that influence illness trajectory and outcome. Over the past decade, studies …

Probiotics' Effects in the Treatment of Anxiety and Depression: A Comprehensive Review of 2014–2023 Clinical Trials

E Merkouris, T Mavroudi, D Miliotas, D Tsiptsios… - Microorganisms, 2024 - mdpi.com
Changes in the gut microbiome can affect cognitive and psychological functions via the
microbiota–gut–brain (MGB) axis. Probiotic supplements are thought to have largely positive …

A microbial-based approach to mental health: the potential of probiotics in the treatment of depression

D Johnson, V Letchumanan, CC Thum… - Nutrients, 2023 - mdpi.com
Probiotics are currently the subject of intensive research pursuits and also represent a multi-
billion-dollar global industry given their vast potential to improve human health. In addition …

Microbiome-gut-brain axis: probiotics and their association with depression

MS Cepeda, EG Katz… - The Journal of …, 2017 - Am Neuropsych Assoc
To assess the association of probiotics with depression, a large population-based cross-
sectional study was conducted. National Health and Nutrition Examination Survey adult …

Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial

AC Schaub, E Schneider… - Translational …, 2022 - nature.com
A promising new treatment approach for major depressive disorder (MDD) targets the
microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions …

A reciprocal link between gut microbiota, inflammation and depression: a place for probiotics?

A Eltokhi, IE Sommer - Frontiers in Neuroscience, 2022 - frontiersin.org
Depression is a severe mental disorder that places a significant economic burden on public
health. The reciprocal link between the trillions of bacteria in the gut, the microbiota, and …