Tumour necrosis factor alpha (TNF-α) and oral squamous cell carcinoma

G Brierly, A Celentano, O Breik, E Moslemivayeghan… - Cancers, 2023 - mdpi.com
Simple Summary TNF-α is of interest in oral squamous cell carcinoma (OSCC), with its
demonstrated presence affecting both tumour and stromal inflammatory cells to enhance …

TNFα signaling is increased in progressing oral potentially malignant disorders and regulates malignant transformation in an oral carcinogenesis model

JW Chadwick, R Macdonald, AA Ali, M Glogauer… - Frontiers in …, 2021 - frontiersin.org
Oral carcinogenesis represents a multi-stage process which encompasses several genetic
and molecular changes that promote the progression of oral potentially malignant disorders …

[HTML][HTML] Oral inflammation promotes oral squamous cell carcinoma invasion

C Goertzen, H Mahdi, C Laliberte, T Meirson… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma (OSCC) represents 95% of oral malignancies and invasion,
and metastasis underlies disease morbidity and mortality. We recently established a direct …

Low‐dose TNF‐α promotes angiogenesis of oral squamous cell carcinoma cells via TNFR2/Akt/mTOR axis

S Li, W Liu, J Liu, Z Yang, L Zhang, F Nie… - Oral …, 2024 - Wiley Online Library
Objectives To assess the role of TNF‐α/TNFR2 axis on promoting angiogenesis in oral
squamous cell carcinoma (OSCC) cells and uncover the underlying mechanisms. Materials …

Role of inflammation in oral carcinogenesis (Part II): CD8, FOXP3, TNF-α, TGF-β and NF-κB expression

MR Piva, LB De Souza… - Oncology …, 2013 - spandidos-publications.com
Due to the frequent presence of inflammation in cases of carcinoma and its use as a
parameter for the assessment of tumor aggressiveness, the role of inflammation in oral …

Evaluation of tumor necrosis factor: Alpha in the saliva of oral cancer, leukoplakia, and healthy controls–A comparative study

M Ameena, R Rathy - Journal of International Oral Health, 2019 - journals.lww.com
Aims: The survival of oral squamous-cell carcinoma (OSCC) patients remains poor despite
recent treatment advances. A sensitive and specific biomarker is important in screening high …

Tumor necrosis factor‐α promoter polymorphism is associated with susceptibility to oral squamous cell carcinoma

CJ Liu, YK Wong, KW Chang, HC Chang… - Journal of oral …, 2005 - Wiley Online Library
Background: Oral squamous cell carcinoma (OSCC) is one of the leading cancers in most
Asian countries. Alterations of immune function have been detected in OSCC patients. The …

Proinflammatory cytokine TNFα promotes HPV-associated oral carcinogenesis by increasing cancer stemness

HS Hong, J Akhavan, SH Lee, RH Kim… - International Journal of …, 2020 - nature.com
High-risk human papillomaviruses (HPVs) are involved in the development of several
human cancers, including oropharyngeal squamous cell carcinomas. However, many …

TNF‐α Drives Matrix Metalloproteinase‐9 in Squamous Oral Carcinogenesis

L Hohberger, BRK Wuertz, H Xie, T Griffin… - The …, 2008 - Wiley Online Library
Abstract Objectives/Hypothesis: It is well known that invasion is a seminal event in the
progression of oral and other head and neck carcinoma sites. We have previously …

[HTML][HTML] Salivary tumour necrosis factor-α as a biomarker in oral leukoplakia and oral squamous cell carcinoma

G Deepthi, SRK Nandan… - Asian Pacific journal of …, 2019 - ncbi.nlm.nih.gov
Background: Oral cancer is one of the life threatening disease which requires an availability
of a biomarker for its early detection and also for effective treatment strategies. The current …