Motor dysfunction as an intermediate phenotype across schizophrenia and other psychotic disorders: progress and perspectives
Primary motor abnormalities (PMA), as found in patients with schizophrenia, are
quantitatively and qualitatively distinct markers of motor system abnormalities. PMA have …
quantitatively and qualitatively distinct markers of motor system abnormalities. PMA have …
Motor dysfunction within the schizophrenia-spectrum: a dimensional step towards an underappreciated domain
D Hirjak, PA Thomann, KM Kubera, ND Wolf… - Schizophrenia …, 2015 - Elsevier
At the beginning of the 20th century, genuine motor abnormalities (GMA) were considered to
be intricately linked to schizophrenia. Subsequently, however, GMA have been increasingly …
be intricately linked to schizophrenia. Subsequently, however, GMA have been increasingly …
Psychomotor symptoms of schizophrenia map on the cerebral motor circuit
S Walther - Psychiatry Research: Neuroimaging, 2015 - Elsevier
Schizophrenia is a devastating disorder thought to result mainly from cerebral pathology.
Neuroimaging studies have provided a wealth of findings of brain dysfunction in …
Neuroimaging studies have provided a wealth of findings of brain dysfunction in …
Motor dysfunction and sensorimotor cortex activation changes in schizophrenia: a study with functional magnetic resonance imaging
J Schröder, M Essig, K Baudendistel, T Jahn, I Gerdsen… - Neuroimage, 1999 - Elsevier
Recent studies demonstrate a diminished activation of the sensorimotor cortex and
supplementary motor area (SMA) in schizophrenia which may be involved in the …
supplementary motor area (SMA) in schizophrenia which may be involved in the …
Supplementary motor area (SMA) volume is associated with psychotic aberrant motor behaviour of patients with schizophrenia
K Stegmayer, H Horn, A Federspiel, N Razavi… - Psychiatry Research …, 2014 - Elsevier
We aimed to investigate whether aberrant motor behavior in schizophrenia was associated
with structural alterations in the motor system. Whole brain voxel based morphometry of …
with structural alterations in the motor system. Whole brain voxel based morphometry of …
[HTML][HTML] Beyond boundaries: in search of an integrative view on motor symptoms in schizophrenia
Schizophrenia is typically conceived as an illness characterized by positive, negative, and
cognitive symptoms. However, most schizophrenia patients also display a wide range of …
cognitive symptoms. However, most schizophrenia patients also display a wide range of …
Motor dysfunction as research domain in the period preceding manifest schizophrenia: a systematic review
D Hirjak, A Meyer-Lindenberg, KM Kubera… - Neuroscience & …, 2018 - Elsevier
Schizophrenia is a severe behavioral syndrome of neurodevelopmental nature marked by
primary or genuine motor abnormalities (GMA), which refer to spontaneous and medication …
primary or genuine motor abnormalities (GMA), which refer to spontaneous and medication …
Altered cortico-basal ganglia motor pathways reflect reduced volitional motor activity in schizophrenia
Little is known about the neurobiology of hypokinesia in schizophrenia. Therefore, the aim of
this study was to investigate alterations of white matter motor pathways in schizophrenia and …
this study was to investigate alterations of white matter motor pathways in schizophrenia and …
Relationship of neuromotor disturbances to psychosis symptoms in first-episode neuroleptic-naive schizophrenia patients
L Cortese, MP Caligiuri, AK Malla, R Manchanda… - Schizophrenia …, 2005 - Elsevier
From the very inception of the modern diagnostic scheme for psychotic disorders,
abnormalities in motor function have been observed in these conditions. Despite …
abnormalities in motor function have been observed in these conditions. Despite …