Background: Atrial fibrillation (AF) is one of the most common cardiac arrhythmias, and in
some patients, the disease is inheritable. Hereditary aspects of AF, however, remain not fully …

Introduction; Atrial fibrillation (AF) is the most common cardiac arrhythmia occurring in the
general population. Recently, several gene mutations associated with ion channels were …

Background Atrial fibrillation (AF) is one of the most common cardiac arrhythmias. In some
patients, the disease is inheritable; however, hereditary aspects of AF remain not fully …

Background Atrial fibrillation (AF), the most common cardiac arrhythmia, is characterised by
rapid and irregular contraction of the atrium. The risk of AF increases with age and AF …

Aims Genetic factors may be important in the development of atrial fibrillation (AF) in the
young. KCNA5 encodes the potassium channel α-subunit KV1. 5, which underlies the …

Background: Family history is a risk factor for atrial fibrillation (AF). We report here a 3-
generation Caucasian family with familial AF and a highly dysfunctional mutation in KCNQ1 …

Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice.
We first reported an S140G mutation of KCNQ1, an α subunit of potassium channels, in one …

Susceptibility to atrial fibrillation (AF) may have a genetic etiology as evidenced by the
association of familial AF with mutations in KCNQ1 and other genes. We re-sequenced …

Common atrial fibrillation (AF) is a complex disease, and its pathogenesis involves multiple
genetic factors, environmental factors, and interactions among these factors. Genetic factors …

KCNQ1 encodes the voltage-gated α-subunit of the IKs channel complex (Kv7. 1), and
KCNQ1 mutations are associated with multiple arrhythmia syndromes. Over the past 12 …