The role of caveolin-1 in human breast cancer

N Patani, LA Martin, JS Reis-Filho… - Breast cancer research and …, 2012 - Springer
Caveolin-1 is the essential constituent protein of specialised plasma membrane
invaginations called caveolae. The unique topology of caveolin-1 facilitates the role of …

Caveolin involvement and modulation in breast cancer

MN Aoki, MK Amarante, J MM Oda… - Mini Reviews in …, 2011 - ingentaconnect.com
Caveolae are highly enriched in numerous membrane-bound proteins and caveolin-1 is
their major component. Caveolae and caveolin proteins are involved in a variety of cellular …

Caveolin in breast cancer

T Bouras, MP Lisanti, RG Pestell - Cancer biology & therapy, 2004 - Taylor & Francis
Caveolin-1 is the principle structural protein of caveolae, sphingolipid and cholesterolrich
invaginations of the plasma membrane involved in vesicular trafficking and signal …

Caveolin-1 and breast cancer: a new clinical perspective

I Mercier, MP Lisanti - Caveolins and Caveolae: Roles in Signaling and …, 2012 - Springer
The current chapter focuses on the role of Caveolin-1 (Cav-1) in cellular growth with an
emphasis on its implication in breast cancer initiation, progression, clinical prognosis and as …

Stromal cell expression of caveolin-1 predicts outcome in breast cancer

EK Sloan, DR Ciocca, N Pouliot, A Natoli… - The American journal of …, 2009 - Elsevier
Caveolin-1 has been linked to tumor progression and clinical outcome in breast cancer, but
a clear resolution of its role as a prognostic marker is lacking. We assessed caveolin-1 …

Caveolin-1 expression in benign and malignant lesions of the breast

C Liedtke, C Kersting, H Bürger, L Kiesel… - World journal of surgical …, 2007 - Springer
Background Caveolin-1 is thought to have an important impact on both signal transduction
and mediation of intracellular processes. Furthermore, it has been suggested that Caveolin …

Non-existence of caveolin-1 gene mutations in human breast cancer

N Patani, MB Lambros, R Natrajan, KJ Dedes… - Breast cancer research …, 2012 - Springer
Caveolin-1 is the principal constituent protein of caveolae, which are specialised plasma
membrane invaginations with diverse biological roles. Caveolin-1 is suggested to have …

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (−/−) null …

H Lee, DS Park, B Razani, RG Russell… - The American journal of …, 2002 - Elsevier
Caveolin-1 (Cav-1) is the principal structural protein of caveolae membranes that are found
in most cells types, including mammary epithelial cells. Recently, we mapped the human …

Caveolin-1 inhibits breast cancer growth and metastasis

EK Sloan, KL Stanley, RL Anderson - Oncogene, 2004 - nature.com
Caveolin-1 was identified in a screen for genes involved in breast cancer progression.
Caveolin-1 is the major protein component of caveolae, flask-shaped invaginations found in …

Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype

SE Elsheikh, AR Green, EA Rakha, RM Samaka… - British journal of …, 2008 - nature.com
Abstract Caveolin-1 (CAV1) and caveolin 2 (CAV2) are the principal structural proteins of
caveolae, sphingolipid and cholesterol-rich invaginations of the plasma membrane involved …