DNA methylation in newborns conceived by assisted reproductive technology
Assisted reproductive technology (ART) may affect fetal development through epigenetic
mechanisms as the timing of ART procedures coincides with the extensive epigenetic …
mechanisms as the timing of ART procedures coincides with the extensive epigenetic …
Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
B Novakovic, S Lewis, J Halliday, J Kennedy… - Nature …, 2019 - nature.com
More than 7 million individuals have been conceived by Assisted Reproductive
Technologies (ART) and there is clear evidence that ART is associated with a range of …
Technologies (ART) and there is clear evidence that ART is associated with a range of …
Association of medically assisted reproduction with offspring cord blood DNA methylation across cohorts
D Caramaschi, J Jungius, CM Page… - Human …, 2021 - academic.oup.com
STUDY QUESTION Is cord blood DNA methylation associated with having been conceived
by medically assisted reproduction? SUMMARY ANSWER This study does not provide …
by medically assisted reproduction? SUMMARY ANSWER This study does not provide …
Comparison of genome-wide and gene-specific DNA methylation between ART and naturally conceived pregnancies
N Melamed, S Choufani, LE Wilkins-Haug, G Koren… - Epigenetics, 2015 - Taylor & Francis
Data linking assisted reproductive technologies (ART) with aberrant DNA methylation is
limited and inconclusive. In addition, most studies to date have analyzed only a small …
limited and inconclusive. In addition, most studies to date have analyzed only a small …
Impact of assisted reproduction, infertility, sex and paternal factors on the placental DNA methylome
S Choufani, AL Turinsky, N Melamed… - Human molecular …, 2019 - academic.oup.com
Abstract Children conceived using Assisted Reproductive Technologies (ART) have a
higher incidence of growth and birth defects, attributable in part to epigenetic perturbations …
higher incidence of growth and birth defects, attributable in part to epigenetic perturbations …
DNA methylation patterns within whole blood of adolescents born from assisted reproductive technology are not different from adolescents born from natural …
B Penova-Veselinovic, PE Melton… - Human …, 2021 - academic.oup.com
STUDY QUESTION Do the epigenome-wide DNA methylation profiles of adolescents born
from ART differ from the epigenome of naturally conceived counterparts? SUMMARY …
from ART differ from the epigenome of naturally conceived counterparts? SUMMARY …
DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids
The number of children born since the origin of Assisted Reproductive Technologies (ART)
exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been …
exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been …
DNA methylation signatures in cord blood of ICSI children
Abstract STUDY QUESTION Does ICSI induce specific DNA methylation changes in the
resulting offspring? SUMMARY ANSWER Although several thousand analyzed CpG sites …
resulting offspring? SUMMARY ANSWER Although several thousand analyzed CpG sites …
DNA methylation in offspring conceived after assisted reproductive techniques: a systematic review and meta-analysis
R Cannarella, A Crafa, LM Mongioì, L Leggio… - Journal of clinical …, 2022 - mdpi.com
Background: In the last 40 years, assisted reproductive techniques (ARTs) have emerged as
potentially resolving procedures for couple infertility. This study aims to evaluate whether …
potentially resolving procedures for couple infertility. This study aims to evaluate whether …
DNA methylation differences between in vitro- and in vivo-conceived children are associated with ART procedures rather than infertility
Background We, and others, have demonstrated previously that there are differences in
DNA methylation and transcript levels of a number of genes in cord blood and placenta …
DNA methylation and transcript levels of a number of genes in cord blood and placenta …