From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I

M Naghavi, P Libby, E Falk, SW Casscells, S Litovsky… - Circulation, 2003 - Am Heart Assoc
Atherosclerotic cardiovascular disease results in> 19 million deaths annually, and coronary
heart disease accounts for the majority of this toll. Despite major advances in treatment of …

Vulnerable plaques and patients: state-of-the-art

M Tomaniak, Y Katagiri, R Modolo… - European heart …, 2020 - academic.oup.com
Despite advanced understanding of the biology of atherosclerosis, coronary heart disease
remains the leading cause of death worldwide. Progress has been challenging as half of the …

Vulnerable plaque: definition, diagnosis, and treatment

PR Moreno - Cardiology clinics, 2010 - cardiology.theclinics.com
Cardiovascular disease is by far the main cause of death in the world. In the United States,
every 30 seconds 1 person experiences a heart attack, and the incidence is increasing …

The myth of the “vulnerable plaque” transitioning from a focus on individual lesions to atherosclerotic disease burden for coronary artery disease risk assessment

A Arbab-Zadeh, V Fuster - Journal of the American College of Cardiology, 2015 - jacc.org
The cardiovascular science community has pursued the quest to identify vulnerable
atherosclerotic plaque in patients for decades, hoping to prevent acute coronary events …

Coronary atherosclerotic vulnerable plaque: current perspectives

C Stefanadis, CK Antoniou, D Tsiachris… - Journal of the American …, 2017 - Am Heart Assoc
Atherosclerosis is the most common form of vascular disease and constitutes the major
cause of death, with 17.5 million related deaths annually (31% of global mortality). 1 …

Vulnerable and dangerous coronary plaques

AP Schroeder, E Falk - Atherosclerosis, 1995 - Elsevier
The clinical presentation and prognosis of coronary atherosclerosis depend more on plaque
type than on plaque size. Stable plaques may narrow the arterial lumen and cause stable …

The vulnerable atherosclerotic plaque: scope of the literature

AA Alsheikh-Ali, GD Kitsios, EM Balk… - Annals of internal …, 2010 - acpjournals.org
The scope of recent literature on the concept of “vulnerable plaque” was reviewed by
examining 463 abstracts of primary and review articles identified through MEDLINE (2003 to …

Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research

P Gaba, BJ Gersh, J Muller, J Narula… - Nature Reviews …, 2023 - nature.com
Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

Early detection and treatment of the vulnerable coronary plaque: can we prevent acute coronary syndromes?

MJ Bom, DJ Van Der Heijden, E Kedhi… - Circulation …, 2017 - Am Heart Assoc
Early identification and treatment of the vulnerable plaque, that is, a coronary artery lesion
with a high likelihood of rupture leading to an acute coronary syndrome, have gained great …

New developments in the detection of vulnerable plaque

M Naghavi, M Madjid, MR Khan… - Current atherosclerosis …, 2001 - Springer
Failure of coronary angiography (luminography) in prediction of future acute coronary
syndromes has cast a shadow of doubt over the value of this old gold-standard technique …