The nuclear lamina is a key structural element of the metazoan nucleus. However, the
structural organization of the major proteins composing the lamina is poorly defined. Using …

The nuclear lamina is an intermediate filament meshwork adjacent to the inner nuclear
membrane (INM) that plays a critical role in maintaining nuclear shape and regulating gene …

The nuclear lamina is an important determinant of nuclear architecture. Mutations in A-type
but not B-type lamins cause a range of human genetic disorders, including muscular …

The nuclear lamina is a meshwork of intermediate-type filament proteins (lamins) that lines
the inner nuclear membrane. The lamina is proposed to be an important determinant of …

We have applied the fluorescence loss of intensity after photobleaching (FLIP) technique to
study the molecular dynamics and organization of nuclear lamin proteins in cell lines stably …

Nuclear lamins were originally described as the main constituents of the nuclear lamina, a
filamentous meshwork closely associated with the inner nuclear membrane. However, within …

The nuclear lamina is an important structural determinant for the nuclear envelope as a
whole, attaching chromatin domains to the nuclear periphery and localizing some nuclear …

The nuclear lamina is a universal feature of metazoan nuclear envelopes (NEs)[1]. In
mammalian cells, it appears as a 10–30 nm filamentous layer at the nuclear face of the inner …

The behavior of chimeric proteins consisting of A-type lamins and green fluorescent protein
(GFP) was studied to investigate the localization and dynamics of nuclear lamins in living …

The nuclear lamina is a protein meshwork that lines the nuclear envelope in metazoan cells.
It is composed largely of a polymeric assembly of lamins, which comprise a distinct …