[HTML][HTML] Mitochondrial quality control in diabetic cardiomyopathy: from molecular mechanisms to therapeutic strategies

C Cai, F Wu, J He, Y Zhang, N Shi, X Peng… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
In diabetic cardiomyopathy (DCM), a major diabetic complication, the myocardium is
structurally and functionally altered without evidence of coronary artery disease …

Mitochondrial quality control mechanisms as molecular targets in diabetic heart

X Chang, Y Li, C Cai, F Wu, J He, Y Zhang, J Zhong… - Metabolism, 2022 - Elsevier
Mitochondrial dysfunction has been regarded as a hallmark of diabetic cardiomyopathy. In
addition to their canonical metabolic actions, mitochondria influence various other aspects of …

[HTML][HTML] Targeting mitochondrial quality control for diabetic cardiomyopathy: therapeutic potential of hypoglycemic drugs

Y Zhou, W Suo, X Zhang, J Liang, W Zhao… - Biomedicine & …, 2023 - Elsevier
Diabetic cardiomyopathy is a chronic cardiovascular complication caused by diabetes that is
characterized by changes in myocardial structure and function, ultimately leading to heart …

[HTML][HTML] The role of mitochondrial abnormalities in diabetic cardiomyopathy

SA Dabravolski, NK Sadykhov, AG Kartuesov… - International Journal of …, 2022 - mdpi.com
Diabetic cardiomyopathy (DCM) is defined as the presence in diabetic patients of abnormal
cardiac structure and performance (such as left ventricular hypertrophy, fibrosis, and …

[HTML][HTML] Mitochondrial mechanisms in diabetic cardiomyopathy

J Gollmer, A Zirlik, H Bugger - Diabetes & metabolism …, 2020 - synapse.koreamed.org
Mitochondrial medicine is increasingly discussed as a promising therapeutic approach,
given that mitochondrial defects are thought to contribute to many prevalent diseases and …

[HTML][HTML] Novel insights into the role of mitochondria in diabetic cardiomyopathy: molecular mechanisms and potential treatments

F Zhi, Q Zhang, L Liu, X Chang, H Xu - Cell Stress and Chaperones, 2023 - Elsevier
Diabetic cardiomyopathy describes decreased myocardial function in diabetic patients in the
absence of other heart diseases such as myocardial ischemia and hypertension. Recent …

[HTML][HTML] The role of mitochondrial biogenesis dysfunction in diabetic cardiomyopathy

LC Tao, T Wang, L Zheng, F Hua… - Biomolecules & …, 2022 - ncbi.nlm.nih.gov
Diabetic cardiomyopathy (DCM) is described as abnormalities of myocardial structure and
function in diabetic patients without other well-established cardiovascular factors. Although …

[HTML][HTML] Mitochondrial dysfunction in diabetic cardiomyopathy

JG Duncan - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2011 - Elsevier
Cardiovascular disease is common in patients with diabetes and is a significant contributor
to the high mortality rates associated with diabetes. Heart failure is common in diabetic …

Mitochondrial quality control in the diabetic heart

Q Liang, S Kobayashi - Journal of molecular and cellular cardiology, 2016 - Elsevier
Diabetes is a well-known risk factor for heart failure. Diabetic heart damage is closely related
to mitochondrial dysfunction and increased ROS generation. However, clinical trials have …

Mitochondrial dynamics in diabetic cardiomyopathy

CA Galloway, Y Yoon - Antioxidants & redox signaling, 2015 - liebertpub.com
Significance: Cardiac function is energetically demanding, reliant on efficient well-coupled
mitochondria to generate adenosine triphosphate and fulfill the cardiac demand. Predictably …