Guanine quadruplex (GQ) is a noncanonical nucleic acid structure formed by guanine-rich
DNA and RNA sequences. Folding of GQs is a complex process, where several aspects …

Guanine quadruplexes (GQs) are non-canonical nucleic acid structures involved in many
biological processes. GQs formed in single-stranded regions often need to be unwound by …

Abstract G-quadruplexes (G4s) are non-canonical nucleic acid structures that fold through
complex processes. Characterization of the G4 folding landscape may help to elucidate …

G-quadruplexes (G4s) are non-canonical nucleic acid structures that fold through complex
processes. Characterization of G4 folding landscape contributes to comprehending G4 roles …

Guanine quadruplexes (G4s) are non-canonical nucleic acids structures common in
important genomic regions. Parallel-stranded G4 folds are the most abundant, but their …

DNA and RNA sequences rich in guanine can fold into noncanonical structures called G-
quadruplexes (GQs), which exhibit a common stem structure of Hoogsteen hydrogen …

The folding kinetics is an important parameter affecting the relevance of DNA and RNA G-
quadruplex (G4) structures in biological processes. Previous studies of the G4 folding …

Abstract Background Guanine quadruplexes (GQs) play vital roles in many cellular
processes and are of much interest as drug targets. In contrast to the availability of many …

Guanine-rich repeat sequences are known to adopt diverse G-quadruplex (G4) topologies.
Determining the unfolding rates of individual G4 species is challenging due to the …

The DNA G-quadruplex (GQ) displays structural polymorphisms, and interactions between
its loops and flanking sequences critically determine which of the diverse GQ conformers is …