A comprehensive review on Thiazole based Conjugates as Anti-cancer Agents

R Rana, N Kumar, HK Gulati, A Sharma… - Journal of Molecular …, 2023 - Elsevier
Over the past few decades, a significant number of anticancer drugs have been developed,
both natural and synthetic. Thiazole, a 5-membered distinctive heterocyclic motif with …

Thiazole moiety: A promising scaffold for anticancer drug discovery

AF Kassem, RH Althomali, MM Anwar… - Journal of Molecular …, 2024 - Elsevier
Over the past few decades, significant advancements in the discovery of anticancer
medicines have yielded various novel agents, both synthetic and natural in origin. Thiazoles …

Synthetic and medicinal perspective of fused-thiazoles as anticancer agents

S Pawar, K Kumar, MK Gupta… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Background: Cancer is second leading disease after cardiovascular disease. Presently,
Chemotherapy, Radiotherapy and use of chemicals are some treatments available these …

Synthetic and anti-cancer activity aspects of 1, 3, 4-thiadiazole containing bioactive molecules: A concise review

VA Obakachi, B Kushwaha, ND Kushwaha… - Journal of Sulfur …, 2021 - Taylor & Francis
Despite significant advances in understanding cancer pathogenesis, it continues to be one
of the leading causes of death. Thus, there is an urgent need for the development of novel …

Recent advances on structural modifications of benzothiazoles and their conjugate systems as potential chemotherapeutics

K Ahmed, S Yellamelli Valli Venkata… - Expert Opinion on …, 2012 - Taylor & Francis
Introduction: Benzothiazole scaffold comprises a bicyclic ring system and is known to exhibit
a wide range of biological properties including antimicrobial and anticancer activities …

Thiazole-containing compounds as therapeutic targets for cancer therapy

PC Sharma, KK Bansal, A Sharma, D Sharma… - European journal of …, 2020 - Elsevier
In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

2-Aminobenzothiazoles in anticancer drug design and discovery

G Huang, T Cierpicki, J Grembecka - Bioorganic chemistry, 2023 - Elsevier
Cancer is one of the major causes of mortality and morbidity worldwide. Substantial
research efforts have been made to develop new chemical entities with improved anticancer …

New horizons in benzothiazole scaffold for cancer therapy: Advances in bioactivity, functionality, and chemistry

PC Sharma, D Sharma, A Sharma, KK Bansal… - Applied Materials …, 2020 - Elsevier
In the pasture of oncology, anticancer agents having advanced modes of action are of great
interest because of increasing chronicity of resistance against anticancer drugs. Heterocyclic …

[PDF][PDF] Thiazoles as potent anticancer agents: A review

S PKN, J Sahoo, SK Paidesetty, GP Mohanta - Indian Drugs, 2016 - researchgate.net
The chemistry of heterocyclic compounds plays a crucial role in the synthesis of medicinals.
This review focuses on the use of the thiazole nucleus for the synthesis of newer drug …

Thiazole in the targeted anticancer drug discovery

A Ayati, S Emami, S Moghimi… - Future medicinal …, 2019 - Future Science
Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …