Atopic dermatitis (AD) is a common relapsing inflammatory skin disorder characterized by
immune-mediated inflammation and epidermal barrier dysfunction. The pathogenesis of AD …

γδT cells mature in the human thymus, and mainly produce IL-17A or IFN-γ, but can also
produce IL-22 and modulate a variety of immune responses. Here, we aimed to evaluate …

Introduction Our group recently demonstrated that IgG modulates αβT cell cytokine
production during the maturation process in the human thymus. The effects of this …

Background Atopic dermatitis (AD) pathogenesis still needs to be elucidated, but invariant
natural killer T (iNKT) cell involvement was already described by several groups. Our group …

Atopic dermatitis (AD) is a chronic disease related to skin disorders that affect individuals in
their childhood and can persist or start in adulthood. Patients affected by this disease …

Atopic dermatitis (AD) is classified as a type 2 disease owing to the majority of type 2
lymphocytes that constitute the skin-infiltrating leukocytes. However, all of the type 1–3 …

Atopic dermatitis (AD) is a recurrent, chronic, and inflammatory skin disease, which
processes with severe itchiness. It often coexists with different atopic diseases. The number …

BACKGROUND: IL-31 is a newly discovered T-cell cytokine that, when overexpressed in
mice, results in pruritus and skin dermatitis resembling human atopic dermatitis (AD) …

Atopic dermatitis is characterized by Th2-dominant immunity. Recently many intracellular
molecules have been reported to regulate cytokine expression and T cell differentiation …

Background: Although CD4+ T cells are known to contribute to the pathology of atopic
dermatitis (AD), the role of T helper 17 cells and interleukin (IL)–17 in skin inflammation …