Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes.

S Ferre, G Von Euler, B Johansson… - Proceedings of the …, 1991 - National Acad Sciences
Since high-affinity adenosine A2 receptors (A2a) are localized exclusively in dopamine-rich
regions in the central nervous system and mediate inhibition of locomotor activity, we have …

Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors

B Kull, S Ferré, G Arslan, P Svenningsson… - Biochemical …, 1999 - Elsevier
Human adenosine A2A and rat dopamine D2 receptors (A2A and D2 receptors) were co-
transfected in Chinese hamster ovary (CHO) cells to study the interactions between two …

Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells

S Ferré, M Torvinen, K Antoniou, E Irenius… - Journal of Biological …, 1998 - ASBMB
The antagonistic interactions between adenosine A 1 and dopamine D 1 receptors were
studied in a mouse Ltk− cell line stably cotransfected with human adenosine A 1 receptor …

Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells

S Dasgupta, S Ferré, B Kull, PB Hedlund… - European journal of …, 1996 - Elsevier
In membrane preparations from rat striatum, where adenosine A2A and dopamine D2
receptors are coexpressed, stimulation of adenosine A2A receptors was found to decrease …

Activation of Adensine A1 and A2A Receptors Modulates Dopamine D2 Receptor‐Induced Responses in Stably Transfected Human Neuroblastoma Cells

H Salim, S Ferré, A Dalal, RA Peterfreund… - Journal of …, 2000 - Wiley Online Library
Adenosine can influence dopaminergic neuro‐transmission in the basal ganglia via
postsynaptic inter‐action between adenosine A2A and dopamine D2 receptors. We have …

Dopamine denervation leads to an increase in the intramembrane interaction between adenosine A2 and dopamine D2 receptors in the neostriatum

S Ferré, K Fuxe - Brain research, 1992 - Elsevier
We have previously found, in striatal membrane preparations from young (2 months old)
rats, that stimulation of adenosine A 2 receptors (with the selective adenosine A 2 agonist …

Postsynaptic antagonistic interaction between adenosine A1, and dopamine D1 receptors

S Ferré, P Popoli, L Giménez-Llort, UB Finnman… - …, 1994 - journals.lww.com
BEHAVIOURAL, AND biochemical evidence for the existence of a powerful specific
postsynaptic interaction between adenosine A 1, and dopamine D 1 receptors in the …

Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum

JS Fink, DR Weaver, SA Rivkees, RA Peterfreund… - Molecular Brain …, 1992 - Elsevier
A cDNA fragment homologous to other G protein-coupled receptors was isolated from rat
brain using the PCR method and demonstrated to be abundantly expressed in striatum …

Functional Uncoupling of Adenosine A2A Receptors and Reduced Response to Caffeine in Mice Lacking Dopamine D2Receptors

NR Zahniser, JK Simosky, RD Mayfield… - Journal of …, 2000 - Soc Neuroscience
Dopamine D2 receptors (Rs) and adenosine A2ARs are coexpressed on striatopallidal
neurons, where they mediate opposing actions. In agreement with the idea that D2Rs …

Electrophysiological and behavioural evidence for an antagonistic modulatory role of adenosine A2A receptors in dopamine D2 receptor regulation in the rat …

I Strömberg, P Popoli, CE Müller… - European Journal of …, 2000 - Wiley Online Library
It has been shown that striatal adenosine A2A receptors can antagonistically interact with
dopamine D2 receptors at the membrane level leading to a decrease in the affinity and …