[HTML][HTML] Impact of antibiotic administration on blood culture positivity at the beginning of sepsis: a prospective clinical cohort study

CS Scheer, C Fuchs, M Gründling, M Vollmer… - Clinical Microbiology …, 2019 - Elsevier
Objectives Sepsis guidelines recommend obtaining blood cultures before starting anti-
infective therapy in patients with sepsis. However, little is known of how antibiotic treatment …

Blood culture results before and after antimicrobial administration in patients with severe manifestations of sepsis: a diagnostic study

MP Cheng, R Stenstrom, K Paquette… - Annals of internal …, 2019 - acpjournals.org
Background: Administering antimicrobial agents before obtaining blood cultures could
potentially decrease time to treatment and improve outcomes, but it is unclear how this …

[PDF][PDF] Predictors of positive blood cultures in critically ill patients: a retrospective evaluation

M Previsdomini, M Gini, B Cerutti, M Dolina… - Croatian medical …, 2012 - hrcak.srce.hr
Predictors of positive blood cultures in critically ill patients: a retrospective evaluation Page 1
www.cmj.hr Aim To identify predictors of bacteremia in critically ill patients, to evaluate the …

Time to appropriate antibiotic therapy is an independent determinant of postinfection ICU and hospital lengths of stay in patients with sepsis

D Zhang, ST Micek, MH Kollef - Critical care medicine, 2015 - journals.lww.com
Objective: To assess the timing of appropriate antibiotic therapy as a determinant of
postinfection hospital and ICU lengths of stay in patients with sepsis. Design: Single-center …

Culture-negative and culture-positive sepsis: a comparison of characteristics and outcomes

MJG Sigakis, E Jewell, MD Maile, SK Cinti… - Anesthesia & …, 2019 - journals.lww.com
BACKGROUND: The primary objective of this study was to compare the characteristics of
culture-positive and culture-negative status in septic patients. We also determined whether …

Blood cultures in the critical care unit: improving utilization and yield

S Shafazand, AB Weinacker - Chest, 2002 - Elsevier
Sepsis is a common cause of morbidity and death in critically ill patients, and blood culture
samples are often drawn in an effort to identify a responsible pathogen. Blood culture results …

Bacteremic sepsis leads to higher mortality when adjusting for confounders with propensity score matching

L Mellhammar, F Kahn, C Whitlow, T Kander… - Scientific reports, 2021 - nature.com
One can falsely assume that it is well known that bacteremia is associated with higher
mortality in sepsis. Only a handful of studies specifically focus on the comparison of culture …

Guidelines on blood cultures

ML Towns, WR Jarvis, PR Hsueh - Journal of Microbiology, Immunology …, 2010 - Elsevier
Just over one-third of sepsis patients have positive blood cultures, mainly due to inadequate
sampling volumes (50% of adults have< 1.0 CFU/mL blood) and the prior use of antibiotics …

[HTML][HTML] Multiplex real-time PCR and blood culture for identification of bloodstream pathogens in patients with suspected sepsis

H Westh, G Lisby, F Breysse, B Böddinghaus… - Clinical Microbiology …, 2009 - Elsevier
Severe sepsis is increasingly a cause of death. Rapid and correct initial antimicrobial
treatment reduces mortality. The aetiological agent (s) cannot always be found in blood …

Clinical significance of potential contaminants in blood cultures among patients in a medical center.

CC Lee, WJ Lin, HI Shih, CJ Wu, PL Chen… - … , and infection= Wei …, 2007 - europepmc.org
Background and purpose Blood culture is important for the diagnosis of sepsis, but it is
sometimes difficult to differentiate true bacteremia from pseudobacteremia. This study …