A non-invasive method for biological age estimation using frailty phenotype assessment

P Pierleoni, A Belli, R Concetti, L Palma, F Pinti… - Ambient Assisted Living …, 2019 - Springer
The human body has two different ages: a Chronological Age (CA), the actual time a person
has been alive, and a Biological Age (BA), the real age that indicate the decline in health …

Moving towards the detection of frailty with biomarkers: A population health study

L Sargent, M Nalls, A Singleton, P Palta… - Aging cell, 2024 - Wiley Online Library
Aging adults experience increased health vulnerability and compromised abilities to cope
with stressors, which are the clinical manifestations of frailty. Frailty is complex, and efforts to …

[HTML][HTML] Early diagnosis of frailty: Technological and non-intrusive devices for clinical detection

F Anabitarte-García, L Reyes-González… - Ageing research …, 2021 - Elsevier
This work analyses different concepts for frailty diagnosis based on affordable standard
technology such as smartphones or wearable devices. The goal is to provide ideas that go …

Biological age estimation using an eHealth system based on wearable sensors

P Pierleoni, A Belli, R Concetti, L Palma, F Pinti… - Journal of Ambient …, 2021 - Springer
The rapid worldwide aging makes necessary the development of advanced technologies for
the objective identification of diseases and disabilities onset. Accordingly, we need to regard …

A novel, population-specific approach to define frailty

A Montesanto, V Lagani, C Martino, S Dato… - Age, 2010 - Springer
The description of frailty, a syndrome of the elderly due to the decline of homeostatic
capacities, has opened new opportunities in the study of the biological basis of human …

[PDF][PDF] Use of biomarkers

L Rodríguez-Mañas - ON FRAILTY, 2015 - garn-network.org
Expanding the concept of frailty to the clinical settings has raised the concern about the
accuracy of the current definitions for identifying frail individuals (not populations). The usual …

[HTML][HTML] Automated frailty scores: towards clinical implementation

JKL Mak, D Religa, J Jylhävä - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Jonathan KL Mak, Dorota Religa, Juulia Jylhävä www. aging-us. com 4572 AGING
outcomes [5] and also has value in risk stratification in COVID-19 patients [6]. For instance …

Biological frailty index in centenarians

B Arosio, A Geraci, E Ferri, D Mari, M Cesari - Aging Clinical and …, 2022 - Springer
This study measured the subclinical frailty of centenarians by looking at the accumulation of
their biological abnormalities. For this aim, a biological Frailty Index (FI) was computed in …

Current and emerging biomarkers of frailty in the elderly

AA Saedi, J Feehan, S Phu, G Duque - Clinical interventions in …, 2019 - Taylor & Francis
The term “frailty” is used to describe a subset of older adults who appear weaker and more
vulnerable than their age-matched counterparts, despite having similar comorbidities …

[HTML][HTML] A study protocol for development and validation of a clinical prediction model for frailty (ModulEn): a new European Commitment to Tackling Frailty

J Apóstolo, E Bobrowicz-Campos… - Translational …, 2019 - ncbi.nlm.nih.gov
There is a growing need to implement and evaluate the technological solutions that allow
the early detection of age-related frailty and enable assessment of the predictive values of …